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Registros recuperados: 11 | |
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Castro,Jazmin; Araya,Germán; Inostroza,Pamela; Hidalgo,Paulina; González-Ramos,Reinaldo; Sovino,Hugo; Angélica Boric,M.; Fuentes,Ariel; Cecilia Johnson,M.. |
BACKGROUND: Endometriosis, pro-inflammatory and invasive benign disease estrogen dependent, abnormally express in endometria the enzyme P450Arom, positively regulated by steroid factor-1 (SF-1). Our objective was to study the nuclear protein contents of upstream stimulating factor 2 (USF2a and USF2b), a positive regulator of SF-1, throughout the menstrual cycle in eutopic endometria from women with and without (control) endometriosis and the involvement of nuclear estrogen receptors (ER) and G-coupled protein estrogen receptor (GPER)-1 RESULTS: Upstream stimulating factor 2 protein contents were higher in mid (USF2b) and late (USF2a and USF2b) secretory phase in eutopic endometria from endometriosis than control (p < 0.05). In isolated control... |
Tipo: Journal article |
Palavras-chave: USF2; GPER1; Endometriosis; Eutopic endometrium; Estrogen receptor; Estrogen receptor specific agonists; SF-1; P450Arom. |
Ano: 2015 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100056 |
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Rocha,M.G.; Gomes,V.A.; Tanus-Santos,J.E.; Rosa-e-Silva,J.C.; Candido-dos-Reis,F.J.; Nogueira,A.A.; Poli-Neto,O.B.. |
The objective of this prospective study was to determine the plasma levels of nitric oxide (NO) in women with chronic pelvic pain secondary to endometriosis (n=24) and abdominal myofascial pain syndrome (n=16). NO levels were measured in plasma collected before and 1 month after treatment. Pretreatment NO levels (μM) were lower in healthy volunteers (47.0±12.7) than in women with myofascial pain (64.2±5.0, P=0.01) or endometriosis (99.5±12.9, P<0.0001). After treatment, plasma NO levels were reduced only in the endometriosis group (99.5±12.9 vs 61.6±5.9, P=0.002). A correlation between reduction of pain intensity and reduction of NO level was observed in the endometriosis group [correlation = 0.67 (95%CI = 0.35 to 0.85), P<0.0001]. Reduction of NO... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Chronic pelvic pain; Endometriosis; Abdominal myofascial pain syndrome; Nitric oxide; Inflammation; Central sensitization. |
Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000400363 |
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Araujo,F.M.; Meola,J.; Rosa-e-Silva,J.C.; Paz,C.C.P.; Ferriani,R.A.; Nogueira,A.A.. |
Endometriosis is a benign, estrogen-dependent disease with symptoms such as pelvic pain and infertility, and it is characterized by the ectopic distribution of endometrial tissue. The expression of the ID2, PRELP and SMOC2 genes was compared between the endometrium of women without endometriosis in the proliferative phase of their menstrual cycle and the eutopic and ectopic endometrium of women with endometriosis in the proliferative phase. Paired tissue samples from 20 women were analyzed: 10 from endometrial and peritoneal endometriotic lesions and 10 from endometrial and ovarian endometriotic lesions. As controls, 16 endometrium samples were collected from women without endometriosis in the proliferative phase of menstrual cycle. Analysis was performed... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Gene expression; Endometriosis; PRELP; SMOC2; ID2; Real-time PCR. |
Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000700605 |
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Passos,E.P.; Brugnara,L.; Facin,A.C.; Riffel,A.; Lima,G.R.; Freitas,V.; Brandelli,A.. |
The effect of peritoneal fluid (PF) on the human sperm acrosome reaction (AR) was tested. Sperm was pre-incubated with PF and the AR was induced by calcium ionophore A23187 and a neoglycoprotein bearing N-acetylglycosamine residues (NGP). The AR induced by calcium ionophore was inhibited 40% by PF from controls (PFc) and 50% by PF from the endometriosis (PFe) group, but not by PF from infertile patients without endometriosis (PFi). No significant differences were found in the spontaneous AR. When the AR was induced by NGP, pre-incubation with PFc reduced (60%) the percentage of AR, while PFe and PFi caused no significant differences. The average rates of acrosome reactions obtained in control, NGP- and ionophore-treated sperm showed that NGP-induced... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Acrosome reaction; Endometriosis; Infertility; Peritoneal fluid; Sperm. |
Ano: 1999 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000100009 |
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Lima,A.P.; Moura,M.D.; Rosa e Silva,A.A.M.. |
Endometriosis is a progressive estrogen-dependent disease affecting women during their reproductive years. The objective of the present study was to investigate whether endometriosis is associated with stress parameters. We determined cortisol and prolactin levels in serum, peritoneal and follicular fluid from infertile women with endometriosis and fertile women without the disease. The extent of the disease was staged according to the revised American Fertility Society classification (1997). Serum and peritoneal fluid were collected from 49 women aged 19 to 39 years undergoing laparoscopy. Eighteen women had stage I-II endometriosis and 10 had stage III-IV. Controls were 21 women undergoing laparoscopy for tubal sterilization. Follicular fluid was... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Endometriosis; Stress; Infertility; Prolactin; Cortisol. |
Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000800015 |
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Hsieh,Yao-Yuan; Chang,Chi-Chen; Tsai,Fuu-Jen; Peng,Ching-Tien; Yeh,Lian-Shun; Lin,Cheng-Chieh. |
Insulin-like growth factor II (IGF2) has been shown to play a role in abnormal cell growth and carcinogenesis. We investigated if the IGF2 gene Apa I polymorphism at exon 9 was associated with the susceptibility to endometriosis, analyzing 120 women with moderate/severe endometriosis and 103 controls. The genotype frequencies did not differ statistically between the endometriosis (aa = 25.4, ab = 57.4, bb = 17.2%) and control (aa = 20.8 ab = 52.8, bb = 26.4%) groups. The allele frequencies did not differ either: a = 54.1, b = 45.9% among women with endometriosis and a = 47.2, b = 52.8% in the control group. Therefore, no indication was found for an association of this polymorphism with endometriosis susceptibility. |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Endometriosis; Insulin-like growth factor; IGF-2. |
Ano: 2004 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000200006 |
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Batista,Ana Paula Castor; Conceição,Ana Paula Maria da; Moraes,Eleonora de Figueiredo; Teixeira,Álvaro Aguiar Coelho; Wanderley Teixeira,Valéria. |
The present research had the purpose to analyze morphologically the sites of endometrial implants on the external area of the musculature of the anterior abdominal wall of female rats, treated with dexamethasone. For so, these 15 albino female rats were used (Rattus norvegicus albinus), of the lineage Wistar with 90 days of age, that were submitted to the induction of the endometriosis, and divided in the following groups: Group I induced female rats to endometriosis and evaluated after 21 days (control); Group II induced female rats to endometriosis and after 21 days, treated with dexamethasone for 10 days; Group III - induced female rats to endometriosis, and after 21 days, treated with dexamethasone for 15 days. The dexamethasone was administered in... |
Tipo: Journal article |
Palavras-chave: Endometriosis; Dexamethasone; Steriods; Hormones; Metaplasia. |
Ano: 2006 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022006000500008 |
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Registros recuperados: 11 | |
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