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| Registros recuperados: 33 | |
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| Meneghini,Rogério; Gamba,Estêvão C.. |
| Several genome sequencing programs were launched in Brazil by the end of the nineties and the early 2000s.The most important initiatives were supported by the ONSA program (http://watson.fapesp.br/onsa/Genoma3.htm) and aimed at gaining domain in genomic technology and bringing molecular biology to the state of art. Two mainsets of data were collected in the 1996-2007 period to evaluate the results of these genome programs: the scientific production (Scopus and Web of Science databases) and the register of patents (US Patent and Trademark Office), both related to the progress of molecular biology along this period. In regard to the former, Brazil took a great leap in comparison to 17 other developed and developing countries, being only surpassed by China.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Science assessment; Genomics; Scientometrics; Molecular biology. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652011000200031 |
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| CAMPOS-DE QUIROZ,HUGO. |
| Recent technological advancements have substantially expanded our ability to analyze and understand plant genomes and to reduce the gap existing between genotype and phenotype. The fast evolving field of genomics allows scientists to analyze thousand of genes in parallel, to understand the genetic architecture of plant genomes and also to isolate the genes responsible for mutations. Furthermore, whole genomes can now be sequenced. This review addresses these issues and also discusses ways to extract biological meaning from DNA data. Although genomic issuesare addressed from a plant perspective, this review provides insights into the genomic analyses of other organisms |
| Tipo: Journal article |
Palavras-chave: Genomics; Plant breeding; Gene discovery. |
| Ano: 2002 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602002000300013 |
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| Scandalios,J.G.. |
| Molecular oxygen (O2) is the premier biological electron acceptor that serves vital roles in fundamental cellular functions. However, with the beneficial properties of O2 comes the inadvertent formation of reactive oxygen species (ROS) such as superoxide (O2<FONT FACE=Symbol>·-</FONT>), hydrogen peroxide, and hydroxyl radical (OH<FONT FACE=Symbol>·</FONT>). If unabated, ROS pose a serious threat to or cause the death of aerobic cells. To minimize the damaging effects of ROS, aerobic organisms evolved non-enzymatic and enzymatic antioxidant defenses. The latter include catalases, peroxidases, superoxide dismutases, and glutathione S-transferases (GST). Cellular ROS-sensing mechanisms are not well understood, but a number of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Catalase; Aging; Telomeres; Gene regulation; Superoxide dismutase; Genomics. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000700003 |
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| Riaño Pachón, Diego Mauricio; González Estrada, Elizabeth; Alexa, Adrian; Ramírez, Fidel; Vischi Winck, Flavia; Gómez Merino, Fernando, Coord.; Silva Rojas, Hilda Victoria, Coord.; Pérez Rodríguez, Paulino, Coord.. |
| En esta publicación intitulada “Bioinformática: aplicaciones a la genómica y proteómica” se detallan algunos de los avances más sobresalientes de los temas de genómica y proteómica, derivados de un curso internacional sobre el tema, organizado por el Colegio de Postgraduados. Estos avances incluyen aspectos de las dos ciencias ómicas, incluyendo genómica y biología estructural, código R, análisis comparativo y evolución, agrupamiento y minería de datos en R, redes de interacciones entre proteínas y proteómica bioinformática. BIOINFORMATICS : APPLICATIONS TO GENOMICS AND PROTEOMICS. ABSTRACT : In this publication entitled "Bioinformatics: applications to genomics and proteomics" are some of the most salient issues of genomics and proteomics, derived from an... |
| Tipo: Libro |
Palavras-chave: Bioinformática; Proteómica; Genómica; ADN; Proteínas; Modelación; Simulación; Análisis de genómas; Biología estructural; Código R; Análisis comparativo; Minería de datos; Computación aplicada; Bioinformatics; Proteomics; DNA; Proteins; Models; Genomics; Simulation; R Code; Data mining; Computing; Genome analysis. |
| Ano: 2010 |
URL: http://hdl.handle.net/10521/313 |
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| Mehta,Angela; Silva,Marilia Santos; Guidetti-Gonzalez,Simone; Carrer,Helaine; Takita,Marco Aurélio; Martins,Natália F.. |
| Citrus spp. are economically important crops, which in Brazil are grown mainly in the State of São Paulo. Citrus cultures are attacked by several pathogens, causing severe yield losses. In order to better understand this culture, the Millenium Project (IAC Cordeirópolis) was launched in order to sequence Citrus ESTs (expressed sequence tags) from different tissues, including leaf, bark, fruit, root and flower. Plants were submitted to biotic and abiotic stresses and investigated under different development stages (adult vs. juvenile). Several cDNA libraries were constructed and the sequences obtained formed the Citrus ESTs database with almost 200,000 sequences. Searches were performed in the Citrus database to investigate the presence of different... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Citrus; Cell signaling; Genomics. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572007000500003 |
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| Kremer,Frederico Schmitt; McBride,Alan John Alexander; Pinto,Luciano da Silva. |
| Abstract The introduction of next-generation sequencing (NGS) had a significant effect on the availability of genomic information, leading to an increase in the number of sequenced genomes from a large spectrum of organisms. Unfortunately, due to the limitations implied by the short-read sequencing platforms, most of these newly sequenced genomes remained as “drafts”, incomplete representations of the whole genetic content. The previous genome sequencing studies indicated that finishing a genome sequenced by NGS, even bacteria, may require additional sequencing to fill the gaps, making the entire process very expensive. As such, several in silico approaches have been developed to optimize the genome assemblies and facilitate the finishing process. The... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Microbial genetics; Molecular microbiology; Genomics; Microbiology; Draft genomes. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572017000400553 |
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| Haag,Karen Luisa. |
| Abstract Symbioses are ubiquitous and have played an influential role in the evolution of life on Earth. Genomic studies are now revealing a huge diversity of associations among hosts and their microbiotas, allowing us to characterize their complex ecological and evolutionary dynamics. The different transmission modes and the asynchronous cell proliferation of the numerous symbionts associated with one host generate a genomic conflict ought to be solved. Two disputing views have been used to model and predict the outcome of such conflicts. The traditional view is based on community ecology, and considers that selection at the level of individuals is sufficient to explain longstanding associations among species. A new perspective considers that the host and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Genomics; Metagenomics; Microbiota; Symbiosis; Holobiont. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572018000200189 |
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| Alvarenga,Samuel Mazzinghy; Caixeta,Eveline Teixeira; Hufnagel,Bárbara; Thiebaut,Flávia; Maciel-Zambolim,Eunize; Zambolimand,Laércio; Sakiyama,Ney Sussumu. |
| Sequences potentially associated with coffee resistance to diseases were identified by in silico analyses using the database of the Brazilian Coffee Genome Project (BCGP). Keywords corresponding to plant resistance mechanisms to pathogens identified in the literature were used as baits for data mining. Expressed sequence tags (ESTs) related to each of these keywords were identified with tools available in the BCGP bioinformatics platform. A total of 11,300 ESTs were mined. These ESTs were clustered and formed 979 EST-contigs with similarities to chitinases, kinases, cytochrome P450 and nucleotide binding site-leucine rich repeat (NBS-LRR) proteins, as well as with proteins related to disease resistance, pathogenesis, hypersensitivity response (HR) and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Coffea; Data mining; ESTs; Genomics; In silico; Bioinformatics. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572010000400031 |
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| RESENDE, R. M. S.; MARTINS, F. B.; VILELA, M. de M.; MORAES, A. C. L.; FERREIRA, R. C. U.; DÉO, T. G.; MOREIRA, F. A.; PASTINA, M. M.; NODA, R. W.; SOUZA, A. P.. |
| Although Brazil is the major producer and exporter of beef in the world, the rangelands are cultivated with varieties obtained by selection on germplasm and conventional breeding. Only lately genomic information started to be used in the tropical forage breeding programs mostly because of the genome complexity and costs. Urochloa ruziziensis is a sexual autotetraploid forage that has a significant role in integrated systems that are currently important in the agribusiness in certain regions of Brazil and is essential as female parent in other Urochloa spp. breeding programs. Thus, this work intends to use the Genotyping by Sequencing (GBS) approach to identify SNP markers to construct the first map of the species and estimate breeding values for Genomic... |
| Tipo: Folders |
Palavras-chave: Genomics; Genetic markers; Pipelines; Breeding. |
| Ano: 2019 |
URL: http://www.infoteca.cnptia.embrapa.br/infoteca/handle/doc/1120361 |
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| Zarski, Daniel; Thaovi Nguyen,; Le Cam, Aurelie; Montfort, Jerome; Dutto, Gilbert; Vidal, Marie-odile; Fauvel, Christian; Bobe, Julien. |
| Variable and low egg quality is a major limiting factor for the development of efficient aquaculture production. This stems from limited knowledge on the mechanisms underlying egg quality in cultured fish. Molecular analyses, such as transcriptomic studies, are valuable tools to identify the most important processes modulating egg quality. However, very few studies have been devoted to this aspect so far. Within this study, the microarray-based transcriptomic analysis of eggs (of different quality) of sea bass (Dicentrarchus labrax) was performed. An Agilent oligo microarray experiment was performed on labelled mRNA extracted from 16 batches of eggs (each batch obtained from a different female) of sea bass, in which over 24,000 published probe arrays were... |
| Tipo: Text |
Palavras-chave: Microarray; Genomics; Transcriptomics; Aquaculture; Controlled reproduction. |
| Ano: 2017 |
URL: http://archimer.ifremer.fr/doc/00371/48220/48345.pdf |
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| Kazantzidis, Ioannis; Florez-revuelta, Francisco; Dequidt, Mickael; Hill, Natasha; Nebel, Jean-christophe. |
| With the development of applications associated to ego-vision systems, smart-phones, and autonomous cars, automated analysis of videos generated by freely moving cameras has become a major challenge for the computer vision community. Current techniques are still not suitable to deal with real-life situations due to, in particular, wide scene variability and the large range of camera motions. Whereas most approaches attempt to control those parameters, this paper introduces a novel video analysis paradigm, ‘vide-omics’, inspired by the principles of genomics where variability is the expected norm. Validation of this new concept is performed by designing an implementation addressing foreground extraction from videos captured by freely moving cameras.... |
| Tipo: Text |
Palavras-chave: Computer vision; Freely moving camera; Genomics; Foreground detection; Segmentation; Scanlines. |
| Ano: 2018 |
URL: http://archimer.ifremer.fr/doc/00405/51643/52191.pdf |
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| Saavedra, Carlos; Bachere, Evelyne. |
| Interest in bivalve genomics has emerged during the last decade, owing to the importance of these organisms in aquaculture and fisheries and to their role in marine environmental science. Knowledge of bivalve genome structure, function and evolution resulting from 20th century "single gene" approaches is limited, but genomic technologies are called to dramatically increase it. Research based on linkage maps, transcriptomics and proteomics is being carried out to study the genetic and molecular bases of traits of interest in bivalve farming industry, mainly disease susceptibility, tolerance to environmental stress, and growth. The Pacific oyster (Crassostrea gigas) is now the focus of an international genome-sequencing consortium. The use of bivalves in... |
| Tipo: Text |
Palavras-chave: Shellfish toxins; Feeding; Stress; Proteomics; Genomics; Bivalves. |
| Ano: 2006 |
URL: http://archimer.ifremer.fr/doc/2006/publication-1709.pdf |
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| Renault, Tristan. |
| Global mollusc production is continuously increasing and reached 12.8 million tonnes in 2004 representing 28.2 percent of the total world production valued at US$ 9.4 billions. However, cultivated molluscs may suffer from severe mortality outbreaks. Among the possible causes is the occurrence of infectious diseases due to a variety of pathogens including protozoan parasites, bacteria and viruses. Preventing and controlling diseases has become a priority for aquaculture sustainability. However, molluscs are unique in terms of health management. Molluscs like other invertebrates, lack a true adaptative immune system. Vaccination can not be used to protect them against pathogens. Moreover, molluscs are usually reared in the open sea which strongly limits the... |
| Tipo: Text |
Palavras-chave: Diagnosis; Phylogeny; Genomics; Mollluscs; Pathogens. |
| Ano: 2008 |
URL: http://archimer.ifremer.fr/doc/2008/publication-4574.pdf |
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| Hedgecock, Dennis; Gaffney, Patrick M.; Goulletquer, Philippe; Guo, Ximing; Reece, Kimberly; Warr, Gregory. |
| An international community of biologists presents the Pacific oyster Crassostrea gigas as a candidate for genome sequencing. This oyster has global distribution and for the past several years the highest annual production of any freshwater or marine organism (4.2 million metric tons, worth $3.5 billion US). Economic and cultural importance of oysters motivates a great deal of biologic research, which provides a compelling rationale for sequencing an oyster genome. Strong rationales for sequencing the oyster genome also come from contrasts to other genomes: membership in the Lophotrochozoa, an understudied branch of the Eukaryotes and high fecundity, with concomitantly high DNA sequence polymorphism and a population biology that is more like plants than any... |
| Tipo: Text |
Palavras-chave: Genomics; Evolutionary and ecological; Nucleotide diversity; Lophotrochozoa; Crassostrea gigas genome sequence; Pacific oyster. |
| Ano: 2005 |
URL: http://archimer.ifremer.fr/doc/2005/publication-2128.pdf |
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| Besson, Mathieu; Allal, Francois; Chatain, Beatrice; Vergnet, Alain; Clota, Frederic; Ferrari, Sebastien; Vandeputte, Marc. |
| We estimated genetic parameters of feed conversion ratio (FCR) and daily growth coefficient (DGC) using individual phenotypes measured in aquariums under a restricted feeding regime and genomic information on 2,722 SNP markers. The results showed a moderate heritability of both traits (0.26 for FCR and 0.41 for DGC) as well as close to unity negative genetic correlation between them. Thus, FCR of fish in aquariums could be improved by selecting fish for higher DGC. Nevertheless, these results must be taken with caution until we know whether individual FCR measured in aquariums also reflects the FCR of fish reared in groups. |
| Tipo: Text |
Palavras-chave: Feed efficiency; Fish; Genomics. |
| Ano: 2018 |
URL: http://archimer.ifremer.fr/doc/00446/55756/57416.pdf |
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| Registros recuperados: 33 | |
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