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| Registros recuperados: 197 | |
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| SELLERS,Samuel; BILSBORROW,Richard; SALINAS,Victoria; MENA,Carlos. |
| ABSTRACT This paper examines changes over time for a full generation of migrant settlers in the Northern Ecuadorian Amazon (NEA). Data were collected from a 2014 household survey covering a subsample of households surveyed previously in 1990 and 1999. We observed changes in demographic behavior, land use, forest cover, and living conditions. As the frontier develops, human fertility is continuing to decline with contraceptive prevalence rising. Meanwhile, out-migration from colonist households, largely to destinations within the region, persists. More households have secure land tenure than in 1999, and are better off as measured by possession of assets. There is continued growth in pasture, largely at the expense of forest. Farms still serve as an... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Family planning; Deforestation; Livelihoods; Migration. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672017000400321 |
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| DRAKULIC,DANIJELA; VICENTIC,JELENA MARJANOVIC; SCHWIRTLICH,MARIJA; TOSIC,JELENA; KRSTIC,ALEKSANDAR; KLAJN,ANDRIJANA; STEVANOVIC,MILENA. |
| The altered expression of the SOX2 transcription factor is associated with oncogenic or tumor suppressor functions in human cancers. This factor regulates the migration and invasion of different cancer cells. In this study we investigated the effect of constitutive SOX2 overexpression on the migration and adhesion capacity of embryonal teratocarcinoma NT2/D1 cells derived from a metastasis of a human testicular germ cell tumor. We detected that increased SOX2 expression changed the speed, mode and path of cell migration, but not the adhesion ability of NT2/D1 cells. Additionally, we demonstrated that SOX2 overexpression increased the expression of the tumor suppressor protein p53 and the HDM2 oncogene. Our results contribute to the better understanding of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Adhesion; HDM2; Migration; P53; SOX2; Wound healing. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000100389 |
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| Godoy,Mario D.P.; Lacerda,Luiz D. de. |
| Mangroves function as a natural coastline protection for erosion and inundation, providing important environmental services. Due to their geographical distribution at the continent-ocean interface, the mangrove habitat may suffer heavy impacts from global climate change, maximized by local human activities occurring in a given coastal region. This review analyzed the literature published over the last 25 years, on the documented response of mangroves to environmental change caused by global climate change, taking into consideration 104 case studies and predictive modeling, worldwide. Most studies appeared after the year 2000, as a response to the 1997 IPCC report. Although many reports showed that the world's mangrove area is decreasing due to direct... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Climate; Mangrove; Limits; Migration. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000200651 |
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| Metz,Claudia; Döger,Remziye; Riquelme,Elizabeth; Cortés,Priscilla; Holmes,Christopher; Shaughnessy,Ronan; Oyanadel,Claudia; Grabowski,Catalina; González,Alfonso; Soza,Andrea. |
| BACKGROUND: Glioblastoma is one of the most aggressive cancers of the brain. Malignant traits of glioblastoma cells include elevated migration, proliferation and survival capabilities. Galectins are unconventionally secreted glycan-binding proteins that modulate processes of cell adhesion, migration, proliferation and apoptosis by interacting with beta-galactosides of cell surface glycoproteins and the extracellular matrix. Galectin-8 is one of the galectins highly expressed in glioblastoma cells. It has a unique selectivity for terminally sialylated glycans recently found enhanced in these highly malignant cells. A previous study in glioblastoma cell lines reported that Gal-8 coating a plastic surface stimulates two-dimensional motility. Because in other... |
| Tipo: Journal article |
Palavras-chave: Galectin-8; Glioblastoma; Cancer; Cell cycle; Apoptosis; Proliferation; Migration. |
| Ano: 2016 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602016000100033 |
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| Seo,Hyang‑Hee; Kim,Sang Woo; Lee,Chang Youn; Lim,Kyu Hee; Lee,Jiyun; Choi,Eunhyun; Lim,Soyeon; Lee,Seahyoung; Hwang,Ki‑Chul. |
| Abstract Background Pathologic vascular smooth muscle cell (VSMC) proliferation and migration after vascular injury promotes the development of occlusive vascular disease. Therefore, an effective chemical agent to suppress aberrant proliferation and migration of VSMCs can be a potential therapeutic modality for occlusive vascular disease such as atherosclerosis and restenosis. To find an anti-proliferative chemical agent for VSMCs, we screened an in-house small molecule library, and the selected small molecule was further validated for its anti-proliferative effect on VSMCs using multiple approaches, such as cell proliferation assays, wound healing assays, transwell migration assays, and ex vivo aortic ring assay. Results Among 43 initially screened... |
| Tipo: Journal article |
Palavras-chave: Syk kinase inhibitor; BAY61-3606 VSMC; Proliferation; Migration. |
| Ano: 2017 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602017000100403 |
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| Gan,Zhihua; Han,Kun; Lin,Shuchen; Hu,Haiyan; Shen,Zan; Min,Daliu. |
| Abstract Background Ubiquitin specific peptidase 39 (USP39), an essential factor in the assembly of the mature spliceosome complex, has an aberrant expression in several cancer. However, its function and the corresponding mechanism on human osteosarcoma has not been fully explored yet. Methods The mRNA and DNA copies of USP39 were increased in osteosarcoma cancer tissues compared with the one in human normal tissues according to datasets from the publicly available Oncomine database. A further western blot analysis also demonstrated an aberrant endogenous expression of USP39 in three different osteosarcoma cells. Then lentivirus-mediated short hairpin RNA (shRNA) was designed to silence USP39 in human osteosarcoma cell line U2OS, which is used to test... |
| Tipo: Journal article |
Palavras-chave: Cell cycle; Migration; Osteosarcoma; Proliferation; USP39. |
| Ano: 2017 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602017000100210 |
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| Wang,Limei; Wu,Xiuyin; Wang,Ruolin; Yang,Chengzhe; Li,Zhi; Wang,Cunwei; Zhang,Fenghe; Yang,Pishan. |
| Abstract Background: Bromodomain-containing protein 4 (BRD4) inhibition is a new therapeutic strategy for many malignancies. In this study, we aimed to explore the effect of BRD4 inhibition by JQ1 on in vitro cell growth, migration and invasion of salivary adenoid cystic carcinoma (SACC). Methods: The human normal epithelial cells and SACC cells (ACC-LM and ACC-83) were treated with JQ1 at concentrations of 0, 0.1, 0.5 or 1 μM. Cell Counting Kit-8 (CCK-8) assay was performed to evaluate cell proliferation. Cell apoptosis and cell cycle distribution was evaluated by Flow cytometry. Immunofluorescence staining was used to examine the expression of BRD4 in SACC cells. The quantitative real-time polymerase chain reaction (qRT-PCR) assay and western... |
| Tipo: Journal article |
Palavras-chave: Salivary adenoid cystic carcinoma; BRD4 inhibition; Proliferation; Migration; Epithelial-mesenchymal transition. |
| Ano: 2017 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602017000100213 |
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| Arai,Takaomi; Amalina,Razikin; Bachok,Zainudin. |
| BACKGROUND: In order to understand feeding ecology and habitat use of coral reef fish, fatty acid composition was examined in five coral reef fishes, Thalassoma lunare, Lutjanus lutjanus, Abudefduf bengalensis, Scarus rivulatus and Scolopsis affinis collected in the Bidong Island of Malaysian South China Sea. RESULTS: Proportions of saturated fatty acids (SAFA) ranged 57.2% 74.2%, with the highest proportions in fatty acids, the second highest was monounsaturated fatty acids (MUFA) ranged from 21.4% to 39.0% and the proportion of polyunsaturated fatty acids (PUFA) was the lowest ranged from 2.8% to 14.1%. Each fatty acid composition differed among fishes, suggesting diverse feeding ecology, habitat use and migration during the fishes' life history in the... |
| Tipo: Journal article |
Palavras-chave: Coral fish; Habitat ecology; Migration; South China Sea; Biochemical signature; Malaysia. |
| Ano: 2015 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100013 |
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| Buchegger,Kurt; Ili,Carmen; Riquelme,Ismael; Letelier,Pablo; Corvalán,Alejandro H.; Brebi,Priscilla; Huang,Tim Hui-Ming; Roa,Juan Carlos. |
| BACKGROUND: Reprimo (RPRM), a highly glycosylated protein, is a new downstream effector of p53-induced cell cycle arrest at the G2/M checkpoint, and a putative tumor suppressor gene frequently silenced via methylation of its promoter region in several malignances. The aim of this study was to characterize the epigenetic inactivation and its biological function in BC cell lines. METHODS: The correlation between RPRM methylation and loss of mRNA expression was assessed in six breast cancer cell lines by methylation specific PCR (MSP), 5'-Aza-2'-deoxycytidine treatment and RT-PCR assays. MDA-MB-231 cells were chosen to investigate the phenotypic effect of RPRM in cell proliferation, cell cycle, cell death, cell migration and invasion. RESULTS: In the cancer... |
| Tipo: Journal article |
Palavras-chave: Reprimo; MDA-MB-231; Migration; Invasion. |
| Ano: 2016 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602016000100005 |
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| Barbieri,Edison; Paes,Eduardo Tavares. |
| Birds were censused weekly from January 1999 to January 2001 along Ilha Comprida beach, a barrier island off São Paulo, southeastern Brazil. To evaluate the similarity in the bird's species composition among the weekly surveys, species counts data were arranged on a data matrix with 144 weekly surveys, analyzed following a multivariate analysis protocol. We counted a total of 205,399 individuals and 52 species. Migratory birds were an important component of the avifauna (maximum N = 21,294 individuals and 14 species). The largest numbers of birds were observed during summer, when Nearctic migrants arrive. All 14 of the most common species were migrants, including Calidris alba, Sterna maxima, Charadrius semipalmatus, Sterna hirundo, Thalasseus maximus,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Seabirds; Ecology; Ilha Comprida; Migration; Shorebirds; Sandy beaches; Multivariate analysis. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-06032008000300003 |
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| Barbieri,Edison; Bete,Douglas. |
| Many Neartic seabirds migrate to South America for the non-breeding season, using several key stopover and wintering sites along the Atlantic coast. The Stercorarius pomarinus is a widely distributed seabird found in every Ocean. It is a migratory bird from northern North America that flies southwards. However, there is little information about the occurrence of Stercorarius pomarinus along the São Paulo State coast. Former publications concerning the birds of Iguape- Cananéia- Ilha Comprida estuary have made no mention of the presence of this bird in the region. Thus it is important that forthcoming appearances be recorded. Throughout the bird-sample selection stage, undertaken since 1998 in the Cananéia estuary (25° 02' 44.71" S and 47° 55' 14.58" W) -... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Seabird; Migration; Cananéia; São Paulo; Stercorarius pomarinus. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-06032013000100035 |
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| Mohammed,Ryan Simon; van Oosterhout,Cock; Schelkle,Bettina; Cable,Joanne; McMullan,Mark. |
| Guppies (Poecilia reticulata Peters 1859) in lakes and from captive-bred populations are predicted to show little rheotaxis compared to conspecifics in a stream environment that are regularly exposed to flash floods associated with involuntary downstream migration. Here we test this hypothesis using an artificial stream, examining guppies of two wild riverine populations, one lake population, and one ornamental strain. Guppies from the most upstream riverine habitat show the most pronounced rheotaxis and are less likely to be swept downstream during flooding events. However, there is no significant difference between guppies from the lowland riverine habitat, the Pitch Lake and ornamental strain. We propose that station-keeping behaviours are most strongly... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Guppy/Poecilia reticulata; Rheotaxis; Swimming behaviour; Migration; Natural selection. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-06032012000300006 |
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| Maravilla-Chávez,M. Octavio; Zavala-González,Alfredo; Ortega-Rubio,Alfredo. |
| This paper describes for the first time the relative abundance, population structure and numeric variation of California sea lions in the Gulf of California, Mexico, during four different seasons. The relative abundance estimates varied from the highest 17,162 sea lions in July of 1990 (summer) to a minimum 7,470 in February of 1992 (winter), representing a reduction of 10,000 sea lions. Hypotheses about the migration of part of the population to the Pacific Ocean were compared and discussed against their residency inside the Gulf, and seasonal dispersion of individuals along this inner sea. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Zalophus californianus californianus; Seasonal variations; Relative abundance; Migration; Gulf of California; Mexico. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000100013 |
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| MORAES,Flávio Ruas de; KLEIN Jr.,Manoel Henrique; MORAES,Julieta Rodini Engrácia de. |
| The intraperitoneal inoculation of 3.8 x 10(9) CFU of alive Salmonella typhimurium caused 100% mortality in rats. In these animals a small number of neutrophils migrated to the peritoneal cavity. The intraperitoneal inoculation of the animals with thioglycollate (Tg, 90 mg), carrageenin (Cg, 500 mu g), or killed S. typhimurium (KS, 1.9 x 10(9) CFU) 24 hours before challenge with alive S. typhimurium caused a significant neutrophil migration to the peritoneal cavity (determined 6 hours after challenge) and protected the animals against the lethal effect of the bacteria at a rate of 50%, 83% and 80%, respectively. However, similar treatment of the animals with brain heart infusion broth (BHI, S. typhimurium grout medium) protected the animals by only 23%.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Migration; Neutrophils; Salmonella typhimurium; Peritonitis; Septicemia; Phagocytosis. |
| Ano: 2000 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-95962000000100002 |
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| Registros recuperados: 197 | |
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