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| OLIVEIRA,FERNANDO A. DE; RORATO,VANESSA C.; ALMEIDA-APOLONIO,ADRIANA A.; RODRIGUES,ALLAN B.; BARROS,ALINE L. DE; SANGALLI,ANDRÉIA; ARENA,ARIELLE C.; MOTA,JONAS S.; GRISOLIA,ALEXÉIA B.; OLIVEIRA,KELLY M.P. DE. |
| ABSTRACT Myracrodruon urundeuva is a plant native to Brazil, which is used by the indigenous population for the treatment of candidiasis. The aims of this study were to evaluate the antifungal activity of extract against human vaginal Candida species and evaluate the possible toxicological activities of M. urundeuva. Initially, ethanol extracts, ethyl acetate fractions, and hydroalcoholic fractions of the bark and leaf of M. urundeuva were used to determine the minimum inhibitory concentration. The extracts that showed antifungal activity were characterized by liquid chromatography and subjected to toxicity assessment. Toxic, cytotoxic, genotoxic, and mutagenic testing were performed using Allium cepa and Ames assays with the ethanol extracts of the bark... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Anacardiaceae; Candidiasis; Myracrodruon urundeuva; Traditional medicine. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000502423 |
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| Ferreira,Paulo Michel P.; Farias,Davi F.; Viana,Martônio P.; Souza,Terezinha M.; Vasconcelos,Ilka M.; Soares,Bruno M.; Pessoa,Cláudia; Costa-Lotufo,Letícia V.; Moraes,Manoel O.; Carvalho,Ana F.U.. |
| This study assessed the antiproliferative and cytotoxic potential against tumor lines of ethanolic seed extracts of 21 plant species belonging to different families from Northeastern Brazil. In addition, some underlying mechanisms involved in this cytotoxicity were also investigated. Among the 21 extracts tested, the MTT assay after 72 h of incubation demonstrated that only the ethanolic extract obtained from Myracrodruon urundeuva seeds (EEMUS), which has steroids, alkaloids and phenols, showed in vitro cytotoxic activity against human cancer cells, being 2-fold more active on leukemia HL-60 line [IC50 value of 12.5 (9.5-16.7) μg/mL] than on glioblastoma SF-295 [IC50 of 25.1 (17.3-36.3) μg/mL] and Sarcoma 180 cells [IC50 of 38.1 (33.5-43.4) μg/mL]. After... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antiproliferative potential; Northeastern Brazilian plants; Myracrodruon urundeuva; Sarcoa 180 tumor; Seed extracts. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652011000300023 |
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| Machado,Alessandra Cury; Sartori,Patrícia Fernandes; Damante,Carla Andreotti; Dokkedal,Anne Lígia; Oliveira,Rodrigo Cardoso de. |
| ABSTRACT The aim of this study was to evaluate the effect of ethanolic "aroeira" (Myracrodruon urundeuva) extract on the viability of human gingival fibroblast. For this, fibroblasts (2x103 cells/well) were plated in a 96-well plate and incubated for 24 h; the medium (Eagle's medium modified by Dulbecco - DMEM) supplemented with 10% fetal bovine serum was replaced by DMEM with different ethanolic extract concentration (0, 0.1, 1, 10, 100, and 1000μg / mL). The fibroblast viability was analyzed after 48,72, and 96 h by the neutral red capture test and violet crystal. The "aroeira" extract, at high concentrations (100 and 1000 µg/mL) caused decrease in both cellular viability tests (p<0.05). However, dilutions between 0.1 and 10 µg/mL did not affect the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Medicinal Plant; Fibroblast; Myracrodruon urundeuva; "aroeira"; "aroeira-do-sertão". |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100301 |
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| Almeida,Anna Christina; Sobrinho,Eliane Macedo; Pinho,Lucineia de; Souza,Patrícia Nery Silva; Martins,Ernane Ronie; Duarte,Eduardo Robson; Santos,Hércules Otacílio; Brandi,Igor Viana; Cangussu,Alex Sander; Costa,João Paulo Ramos. |
| O estudo objetivou realizar ensaio toxicológico pré-clínico inicial para investigar a toxicidade das folhas de alecrim-pimenta (Lippia sidoides Cham.), aroeira (Myracrodruon urundeuva Fr. All.) e barbatimão [Stryphnodendron adstringens (Mart.) Coville] e do farelo da casca de pequi (Caryocar brasiliense Camb.), por meio da determinação da dose letal 50% (DL50). Na investigação da DL50, foram utilizados grupos de camundongos Swiss de mesmo sexo (n=150, sendo 30 animais por tratamento) inoculados, por via intraperitoneal, com diluições seriadas do extrato hidroalcoólico das folhas de alecrim, aroeira e barbatimão e do farelo da casca de pequi. Após a inoculação, os animais foram observados por um período de 14 dias, para determinar a quantidade de mortos,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Intoxicação; Plantas medicinais; Camundongos; Intraperitoneal; Lippia sidoides; Myracrodruon urundeuva; Stryphnodendron adstringens Caryocar brasiliense. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782010000100034 |
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| Isquierdo,Eder P.; Caldeira,Daniela S. A.; Siqueira,Valdiney C.; Martins,Elton A. S.; Quequeto,Wellytton D.. |
| ABSTRACT This study aimed to obtain and evaluate thermodynamic properties and hygroscopic equilibrium isotherms of urunday seeds as a function of air relative humidity and temperature, as well as identify the best-fitted mathematical models for adsorption phenomenon. A static-gravimetric method was used to obtain hygroscopic equilibrium moisture content. Seeds were placed in airtight containers with different saturated saline solutions for relative humidity control. These were then kept in BOD incubator chambers at 10, 20, 30, and 40 °C. Hygroscopic equilibrium moisture content decreased as temperature increased, for the same water activity. The Sigma-Copace model best-fitted seed adsorption data for equilibrium water activity intervals between 0.1129 and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Water activity; Isokinetic; Sorption isotherms; Myracrodruon urundeuva; Relative humidity. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69162020000300374 |
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| Abdala,Ludmila; Moraes,Mario Luiz Teixeira de; Rechia,Carem Gledes Vargas; Giorgini,Jarbas Francisco; Sá,Marco Eustáquio de; Polizeli,Maria de Lourdes Teixeira de Moraes. |
| The objectives of this work were to analyze seeds from 20 trees of aroeira (Myracrodruon urundeuva Fr. All.) of a natural population located in the region of Selvíria, State of Mato Grosso do Sul, Brazil, in order to evaluate their protein, lipid and carbohydrate contents, and to estimate their genetic variation. A completely randomized experimental design consisting of 20 treatments (families) was set up, with two replications. Four types of proteins were detected: albumin (35.0 to 107.3 mg/g seed), globulin (3.4 to 9.3 mg/g), prolamin (60.0 to 135.2 mg/g) and glutelin (118.0 to 286.0 mg/g). The lipid content varied between 200 and 334 mg/g seed. The total sugars also varied (26.5 to 46.3 mg/g seed), with a predominance of polyols (arabinitol, mannitol,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Myracrodruon urundeuva; Seed; Proteins; Lipids; Carbohydrates; Evaluation. |
| Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-204X2002000700003 |
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