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Najafdari,Simin; Rezaei,Noorallah; Shafaroodi,Majid Malekzadeh; Ghafari,Soraya; Golalipour,Mohammad Jafar. |
Previous studies have shown the adverse effects of gestational diabetes on hippocampal neuronal density in animal models. This study was conducted to determine the effect of gestational diabetes on retinal ganglionic cell density, the thickness of the retinal layer and apoptotic ganglionic cell density in 28-day-old of rat offspring. In this experimental study, 10 Wistar rat dams were randomly allocated in control and diabetic groups. Gestational diabetes was induced by 40 mg/kg/body weight of streptozotocin at the first day of gestation, intraperitoneally, dams in control group received an equivalent volume normal saline. At postnatal day 28, six offspring of each gestational diabetes and controls were randomly selected, sacrificed and sections (6... |
Tipo: Journal article |
Palavras-chave: Gestational diabetes; Apoptosis; Retinal layer; Ganglionic cells; TUNEL Assay; Rat offspring. |
Ano: 2014 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000400001 |
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