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Registros recuperados: 34 | |
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Papazian-Cabanas,Rodrigo M.; Araújo,Eduardo J.A.; Silva,Aristeu V. da; Sant'Ana,Débora M.G.. |
The effects of acute and chronic infection caused by Toxoplasma gondii on duodenal myenteric neurons were analyzed. Eighteen rats were assigned into four groups: Acute Control Group (ACG, n=4); Acute Experimental Group (AEG, n=4); Chronic Control Group (CCG, n=5); and Chronic Experimental Group (CEG, n=5). Rats from the AEG and CEG were inoculated orally with 105 genotype III (BTU-II strain) tachyzoites of T. gondii isolated from a dog with neurological signs. Acute groups were killed after 24 hours after the inoculation and the chronic groups after 30 days. Whole-mount from the duodenum were stained with Giemsa. The population density of myenteric neurons, as well the body cell, nuclear and cytoplasmic area were analyzed. Both acute and chronic... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Enteric nervous system; Infection; Parasite; Toxoplasmosis. |
Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652012000300016 |
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Feitosa,T.F.; Vilela,V.L.R.; Dantas,E.S.; Souto,D.V.O.; Pena,H.F.J.; Athayde,A.C.R.; Azevêdo,S.S.. |
In the present study we aimed to establish the seroprevalence of T. gondii and N. caninum in stray and domiciled cats from the municipality of Patos, Paraíba state, Brazil. Blood samples were collected from 201 animals: 132 domiciled cats and 69 stray cats. An epidemiological questionnaire was conducted with all cat owners. Indirect immunofluorescent antibody test (IFAT) was performed at cut-offs of 1:16 and 1:50 for T. gondii and N. caninum, respectively. Overall prevalence of seroreagent cats for T. gondii was 43.8%. We found a prevalence of 47.7% in domiciled cats and 36.2% in stray cats. Antibody titers ranged from 1:16 (cut-off) to 1:8192; 1:128 was the most frequent titer. No statistical difference was observed between domiciled cats and stray cats.... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Domiciled cat; Stray cat; Toxoplasmosis; Zoonosis. |
Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352014000401060 |
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Aguiar,D.M.; Amude,A.M.; Santos,L.G.F.; Ribeiro,M.G.; Ueno,T.E.H.; Megid,J.; Paes,A.C.; Alfieri,A.F.; Alfieri,A.A.; Gennari,S.M.. |
O presente estudo relata a ocorrência de co-infecção entre o vírus da cinomose canina (CDV) e Toxoplama gondii em cães com sinais neurológicos. Amostras de soro e tecido nervoso (pos-mortem) de 21 cães, suspeitos de cinomose canina foram analisadas pela Reação de Imunofluorecência indireta (RIFI) para pesquisa de anticorpos contra T. gondii e N. caninum e por RT-PCR para CDV. Dezessete (80,9%) cães foram positivos para o CDV pela RT-PCR e 8 (38,1%) foram positivos para anticorpos contra T. gondii. Sete cães (41,1%) apresentaram-se positivos para ambos agentes, caracterizando processo de co-infecção. Somente 1 (4,7%) cão foi soropositivo para N. caninum (RIFI=100), entretanto este mesmo animal foi positivo para T. gondii (RIFI=4096) e para CDV (RT-PCR). |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Dogs; Canine distemper; Toxoplasmosis; Neospora caninum; Co-infection. |
Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352012000100032 |
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Silva,Cassius Schnell Palhano; Neves,Elizabeth de Souza; Benchimol,Eliezer Israel; Moraes,Danielle Ribeiro de. |
Infection caused by Toxoplasma gondii, toxoplasmosis, is one of the most frequent zoonoses in the world; it normally affects both genders equally. Humans are one of several possible intermediate hosts, and the disease is oligosymptomatic in most cases. Vertical transmission is an important cause of fetal malformation and sequels in newborns. Approximately 10% of postnatal cases present multiple manifestations, ranging from low fever and mild lymphadenopathy to severe encephalitis. In moderate cases, lesions such as retinochoroiditis may emerge during acute infection or even years later. We analyzed 313 cases of toxoplasmosis from 1992 to 2004, including 261 acute cases. Most patients were women (68.1%), and 39% of these were pregnant. Among acute infection... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Toxoplasmosis; Toxoplasma gondii; Survey; Clinical presentation; Retinochoroiditis. |
Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000500016 |
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Sampaio,Barbara Carvalho Fialho; Rodrigues,Jaqueline Polizeli; Meireles,Luciana Regina; Andrade Junior,Heitor Franco de. |
ABSTRACT Introduction: Vaccines are well-established public health interventions with major impacton the prevalence of infectious diseases, but outbreaks are occurring frequently due to pri-mary and secondary failures, despite high coverage. Surveillance of efficacy and duration ofinduced immunity is a difficult task as it requires invasive blood sampling in children andteenagers. Saliva can be an acceptable alternative source of IgG to assess vaccine efficacyand toxoplasmosis incidence. We investigated IgG response for measles, mumps, rubella,and T. gondii in saliva samples of vaccinated young people. Methods: Saliva was collected from 249 public schools students from São Paulo, Brazil, aged7 to 13 years old, during an interactive exhibition on hygiene.... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Vaccine; Prevalence; Non-invasive; Saliva; IgG; Toxoplasmosis. |
Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702020000100051 |
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Lopes-Mori,Fabiana Maria Ruiz; Mitsuka-Breganó,Regina; Bittencourt,Laura Helena França de Barros; Dias,Renata Cristina Ferreira; Gonçalves,Daniela Dib; Capobiango,Jaqueline Dario; Reiche,Edna Maria Vissoci; Morimoto,Helena Kaminami; Freire,Roberta Lemos; Navarro,Italmar Teodorico. |
The aim of the present study was to verify the association between seropositivity for IgG anti-Toxoplasma gondii antibodies and social, economic and environmental variables of pregnant women attending the public health centers of Paraná, Brazil. From January 2007 to July 2010, 2226 pregnant women were interviewed and detection of anti-T. gondii specific IgG and IgM antibodies was performed by chemiluminescence test. Seropositivity for anti-T. gondii IgG was observed in 1151 (51.7%) pregnant women, 29 of which (1.3%) presented IgM reagent with IgG of high avidity. The variables associated with the presence of IgG were residency in the rural area, more than one pregnancy, less than or equal to eight years schooling, low per capita income, age group, raw or... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Seroepidemiology; Prevalence; Toxoplasmosis; Pregnancy. |
Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000400004 |
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Silva,Marcos Gontijo da; Lino Junior,Ruy de Souza; Costa,Tatiane Luiza da; Soares,Joanna D´arc Herzog; Amaral,Waldemar Naves do; Avelino,Mariza Martins; Castro,Ana Maria de. |
Toxoplasmosis is one of the most important diseases of the nervous central system, leading to severe symptoms and, many times, irreversible sequelae. This work demonstrated the main anatomopathological lesions caused by Toxoplasma gondii in brains from experimentally infected BALB/c mice. We analyzed 51 cases of mice that developed toxoplasmosis after experimental infection by intraperitoneal inoculation of blood, amniotic liquid and cerebrospinal fluid from fetuses, newly born children and pregnant women with clinical and laboratory signals of toxoplasmosis. In all experiments where we detected the parasite in mice we also detected pathological lesions in the animal brains with great polymorphism between experiments. Edema was the most found lesion in all... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Toxoplasmosis; Experimental histopathology; Mice brains. |
Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000100012 |
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Libório,Alexandre B.; Silva Jr,Geraldo B.; Silva,Carolina G.C.H.; Lima Filho,Francisco J.C.; Studart Neto,Adalberto; Okoba,Willy; Bruin,Veralice M.S. de; Araújo,Sônia M.H.A.; Daher,Elizabeth F.. |
BACKGROUND: There are no reports on hyponatremia and acute kidney injury (AKI) involved in the course of HIV-related toxoplasmic encephalitis (TE). The main objective of this study was to describe the occurrence of hyponatremia and its relationship with AKI and mortality in HIV-related toxoplasmic encephalitis (TE). METHODS: This was a retrospective cohort study on patients with HIV-related TE. AKI was considered only when the RIFLE (risk, injury, failure, loss, end-stage) criterion was met, after the patient was admitted. RESULTS: A total of 92 patients were included, with a mean age of 36 ± 9 years. Hyponatremia at admission was observed in 43 patients (46.7%), with AKI developing in 25 (27.1%) patients during their hospitalization. Sulfadiazine was the... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Toxoplasmosis; Encephalitis; Hyponatremia; Acute kidney injury; HIV; Mortality. |
Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000600010 |
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Lopes,Fabiana Maria Ruiz; Gonçalves,Daniela Dib; Mitsuka-Breganó,Regina; Freire,Roberta Lemos; Navarro,Italmar Teodorico. |
Toxoplasmosis is caused by an intracellular protozoan, Toxoplasma gondii, which has a wide geographical distribution. The main infection routes are ingestion of cysts from raw or badly-cooked meat, ingestion of oocysts from substrates contaminated with the feces of infected felines and congenital transmission by tachyzoites. The congenital form results in a severe systemic disease, because if the mother is infected for the first time during gestation, she can present a temporary parasitemia that will infect the fetus. Many of the clinical symptoms are seen in congenitally-infected children, from a mild disease to serious signs, such as mental retardation. Early diagnosis during the pregnancy is highly desirable, allowing prompt intervention in cases of... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Toxoplasmosis; Toxoplasma gondii; Congenital transmission; Pregnant women. |
Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000500011 |
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Gonçalves,Daniela Dib; Benitez,Aline; Lopes-Mori,Fabiana Maria Ruiz; Alves,Lucimara Aparecida; Freire,Roberta Lemos; Navarro,Italmar Teodorico; Santana,Maria Aparecida Zanella; Santos,Luís Roberto Alves dos; Carreira,Teresa; Vieira,Maria Luísa; Freitas,Julio Cesar de. |
The aim of this study was to conduct a serological survey for Lyme diseases, brucellosis, leptospirosis and toxoplasmosis and identify the risk variables related to these zoonoses in humans living in the rural area of Jataizinho, state of Parana, Brazil. A total of 63 rural properties were surveyed. Additionally, 207 serum samples collected from these rural area inhabitants were tested for indirect immunofluorescence (IFI) and western blots (WB) were performed to detect Borrelia burgdorferi (sensu lato); a tamponated acidified antigen test (AAT) and 2-mercaptoethanol (2-ME) were used to detect antibodies of Brucella abortus; the microscopic agglutination test (MAT) was carried out to detect antibodies anti-Leptospira spp. and IFI was used to find... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Lyme disease; Leptospirosis; Brucellosis; Toxoplasmosis; Human; Antibody. |
Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000100018 |
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Schroder,Deise Cristine; Stocco,Matias Bassinello; Isoton,Deborah de Arruda; Silva,Carla Patricia Amarante e; Braga,Ísis Assis; Silva,Érica Pereira da; Maciel,Camila do Espírito Santo; Maruyama,Fernanda Harumi; Nakazato,Luciano; Aguiar,Daniel Moura de; Mendonça,Adriane Jorge; Ribeiro,Alexandre Pinto. |
ABSTRACT: This study aimed to evaluate the effects of firocoxib for controlling experimentally-induced breakdown of the blood-aqueous barrier in healthy and Toxoplasma gondii -seropositive cats. Thirty two cats with no ocular abnormalities were used. Groups (n=8/each) were formed with healthy cats that received 5mg g-1 of oral firocoxib (FH) or no treatment (CH) on day 0; seropositive cats for anti -T. gondii specific immunoglobulin G (IgG) were grouped (n=8/each) and treated in a similar fashion (FT and CT). On day 1, cats of all groups received the same treatment protocol, and 1h later, aqueocentesis was performed under general anesthesia (M0). Following 1h, the same procedure was repeated (M1). Quantitation of aqueous humor total protein and... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Aqueous humor; Intraocular inflammation; NSADs; Toxoplasmosis. |
Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782016000601053 |
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Andrade,Márcia Cristina Ribeiro; Coelho,Janice Mery Chicarino de Oliveira; Amendoeira,Maria Regina Reis; Vicente,Regiane Trigueiro; Cardoso,Célia Virgínia Pereira; Ferreira,Paola Cristina Brandão; Marchevsky,Renato Sergio. |
Necropsy findings in three cases of naturally occurring toxoplasmosis in squirrel monkeys (Saimiri sciureus) obtained as wild catches from the Amazon region were described. Histopathological evaluation of the liver, spleen, kidneys and mesenteric lymph nodes showed multiple foci of inflammation and necrosis. Typical, well-defined morphologic Toxoplasma gondii cysts and free forms of the parasite were found by immunoperoxidase staining within inflammatory infiltrates. The presence of T. gondii in the studied colony could severely influence the results of experiments performed in the animals. |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Squirrel monkeys; Neotropical primates; Toxoplasmosis; Immunohistochemical analysis; Serology. |
Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782007000600034 |
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Bresciani,Katia Denise Saraiva; Toniollo,Gilson Hélio; Costa,Alvimar José da; Sabatini,Gustavo Adolfo; Moraes,Flávio Ruas de. |
Eight pregnant mixed breed bitches, serologically negative for Toxoplasma gondii, were divided into three groups. Group I : bitches 01 and 02 (1.0 x 10(7) tachyzoites of Toxoplasma gondii, subcutaneous route); Group II: bitches 03, 04 and 05 (1.5 x 10(4) oocysts, oral route); Group III: bitches 06, 07 and 08 (as control). Clinical and obstetric examinations were conducted twice a day on each bitch, and weekly ultra-sonografic evaluations were performed until the end of pregnancy. From the 2nd day the bitches presented clinical alterations such as fever, nasal flowing, lachrymation, prostration, lymphadenopathy, premature parturition, abortion and fetal death. In Group I, Toxoplasma gondii was isolated from the bitches urine (day 10) and saliva (day 18).... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Toxoplasmosis; Toxoplasma gondii; Pregnant bitches; Pathology. |
Ano: 2001 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782001000600020 |
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Arantes,Tiago Pereira; Lopes,Welber Daniel Zanetti; Ferreira,Roberta Machado; Pieroni,Juliana de Souza Pinto; Pinto,Vanessa Marigo Rocha; Santos,Thaís Rabelo dos; Sakamoto,Claúdio Alessandro; Costa,Alvimar José da. |
The present research aimed to describe possible histopathological alterations in the reproductive system (testicles and epididymis) of male dogs experimentally infected with Toxoplasma gondii. Canines (n=10) serologically negative for T. gondii were selected and distributed into three experimental groups: GI, 3 inoculated with 2.0 x 10(5)P strain oocysts; GII, 3 infected with 1.0 x 10(6)RH strain tachyzoites; and GIII, 4 control dogs. Antibody research (IFAT) against T. gondii was realized. Toxoplasma gondii infection was confirmed by seroconversion of the 6 males infected with tachyzoites and oocysts from postinoculation day (PID) 7 and 14, respectively. At PID 70, all dogs were submitted to orchiectomy and testicle and epididymis samples were collected... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Canine; Experimental infection; Toxoplasmosis; Histopathology; Testicle; Epididymis. |
Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782009000700026 |
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Brandão,Laila Natasha Santos; Rosa,Janaina Marcela Assunção; Kramer,Beatris; Sousa,Alessandra Tammy Hayakawa Ito de; Trevisol,Iara Maria; Silva,Virginia Santiago; Nakazato,Luciano; Dutra,Valéria. |
ABSTRACT: Wild boars (Sus scrofa) have become an important invasive species in all Brazilian regions. Increase in their population causes damage to rural properties, as they invade and destroy crops. To protect their crops and farm animals, producers hunt wild boars and often consume the product without any sanitary control, becoming exposed to various types of pathogens, including Toxoplasma gondii. Sanitary evaluations of these animals are scarce, especially in relation to the protozoan T. gondii. This study aimed to evaluate the occurrence of this pathogen in wild boars in Brazil. We analyzed 122 blood samples from wild boars (blood clots and serum), collected between 2014 and 2016 in five Brazilian states, using polymerase chain reaction (PCR) and... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Toxoplasmosis; Wild boar; Zoonosis. |
Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782019000300500 |
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Registros recuperados: 34 | |
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