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	Provedor de dados BJPS (2) Autor Özdemir,Nurten (2) Dinç,Erdal (1) Tilkan,Günseli Yüksel (1) Tilkan,Müşerref Günseli Yüksel (1) Türkmen,Berna (1) Üstündağ,Özgür (1) Mais... Palavra-chave Binary mixture/tablets. (1) Chitosan (1) Flurbiprofen (1) Hydrochlorothiazide (1) Ionotropic gelation (1) Microsphere (1) Spectral Continuous Wavelets Transform (1) Tripolyphosphate (1) Valsartan (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2017 (2) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Investigation of the parameters affecting the release of flurbiprofen from chitosan microspheres BJPS Tilkan,Müşerref Günseli Yüksel; Özdemir,Nurten. ABSTRACT Flurbiprofen (FLB), a NSAID, widely used for preventing pain generally for arthritis or dental problems. In this study, FLB loaded chitosan microspheres were prepared by ionotropic gelation method. In this method, microspheres were formed by dropping chitosan solutions containing FLB into sodium alginate solutions including sodium tripolyphosphate (TPP). A variety of formulation parameters like drug:polymer ratio, drug concentration, polymer’s molecular weight, polymer concentration, pH and the concentration of TPP solutions, drying method and stirring time were analyzed. The dissolution studies were performed in a shaking water bath in pH 7.4 phosphate buffer saline (PBS) at 37 °C. Laser diffractometer was used for particle size analysis, and... Tipo: Info:eu-repo/semantics/article Palavras-chave: Flurbiprofen; Chitosan; Tripolyphosphate; Ionotropic gelation; Microsphere. Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000400621 Continuous wavelet transform methods for the simultaneous determinations and dissolution profiles of valsartan and hydrochlorothiazide in tablets BJPS Dinç,Erdal; Üstündağ,Özgür; Tilkan,Günseli Yüksel; Türkmen,Berna; Özdemir,Nurten. ABSTRACT Continuous wavelet transform (CWT) was proposed for the simultaneous determination and dissolution profiles of valsartan (VAL) and hydrochlorothiazide (HCT) in tablets, without the use of a chemical separation procedure. The CWT approach was applied to the original UV spectra and their ratio spectra in the optimal wavelength ranges. After testing several wavelet families, Mexican hat function-CWT and Daubechies7-CWT (mexh-CWT and db7-CWT, respectively) were found to be suitable for the transformation of the original UV spectra. In the following procedure, mexh-CWT and Coiflets3-CWT (coif3-CWT) were found to be appropriate for the signal analysis of ratio spectra (RS) of VAL/HCT and HCT/VAL. Calibration graphs for VAL and HCT were obtained by... Tipo: Info:eu-repo/semantics/article Palavras-chave: Spectral Continuous Wavelets Transform; Valsartan; Hydrochlorothiazide; Binary mixture/tablets.. Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000100618 Registros recuperados: 2 Primeira ... 1 ... Última

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