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	Provedor de dados OAK (7) Autor 橋本, 誠 (7) Hashimoto, Makoto (4) Hatanaka, Yasumaru (2) HASHIMOTO, MAKOTO (1) HASHIMOTO, Makoto (1) HATANAKA, Yasumaru (1) Hayashi, Yuka (1) KATO, Yuh-hi (1) Murashige, Ryo (1) Mais... Palavra-chave Diazirine (2) Photoaffinity labeling (2) Bioorganic chemistry (1) Chemical biology (1) Hydrogenation (1) Structure-activity relationships (1) Wilkinson’s catalyst (1) ジアジリン (1) ペプチド (1) 光アフィニティーラベル (1) 化学修飾 (1) 核酸－蛋白質相互作用 (1) 構造活性相関 (1) 機能解析 (1) 機能部位解析 (1) Mais... Ano 2009 (1) 2008 (4) 2007 (1) 2005 (1) País Japan (7) Idioma Inglês (4) Japonês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 7 Primeira ... 1 ... Última トリフルオロメチルフェニルジアジリンを用いた光アフィニティーラベル法の進歩 OAK 橋本, 誠. http://www.jsbba.or.jp/pub/pub_journal_kasei.html Ano: 2005 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/2705 Asymmetric and efficient synthesis of homophenylalanine derivatives via Friedel-Crafts reaction with trifluoromethanesulfonic acid OAK Murashige, Ryo; Hayashi, Yuka; Hashimoto, Makoto; 橋本, 誠. An efficient Friedel-Crafts reaction of TFA-Asp(Cl)-OMe and stoichiometric amounts of benzene was established by using neat trifluoromethanesulfonic acid (TfOH) as solvent and catalyst under a mild condition. This methodology has been applied to many aromatic compounds and enabled synthesis of several homophenylalanine derivatives. Ano: 2008 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/2703 Recent progress in diazirine based photoaffinity labeling OAK Hashimoto, Makoto; Hatanaka, Yasumaru; 橋本, 誠. Based on the recent development of molecular biology, the investigation of biofunctional machinery at their ligand accepting interface has become one of the challenging and important subject of post-genome field. The technique of photoaffinity labeling has become increasingly appreciated as a powerful methodology for the purpose. This micro review focused synthesis of trifluoromethylphenyldiazirine, which is one of the most promising photophore, and its application to the biomolecules. Palavras-chave: Photoaffinity labeling; Chemical biology; Bioorganic chemistry; Structure-activity relationships; Diazirine. Ano: 2008 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/2700 Selective Hydrogenation of Alkene in (3-Trifluoromethyl) Phenyldiazirine Photophor with Wilkinson’s Catalyst for Photoaffinity Labeling OAK HASHIMOTO, Makoto; KATO, Yuh-hi; HATANAKA, Yasumaru; 橋本, 誠. Selective hydrogenation of carbon–carbon double bond in the presence of nitrogen–nitrogen double bond in (3-trifluoromethyl) phenyldiazirine achieved with Wilkinson's catalyst. Palavras-chave: Photoaffinity labeling; Diazirine; Hydrogenation; Wilkinson’s catalyst. Ano: 2007 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3611 核酸-生体高分子相互作用解析を目指した光アフィニティーラベル法の開発 OAK 橋本, 誠; HASHIMOTO, MAKOTO. 2007年度～2008年度科学研究費補助金基盤研究(C) 研究成果報告書19510210 Palavras-chave: 光アフィニティーラベル; ジアジリン; 核酸－蛋白質相互作用; 構造活性相関; 機能部位解析. Ano: 2009 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/2749 A novel biotinylated diazirinyl ceramide analogue for photoaffinity labeling OAK Hashimoto, Makoto; Hatanaka, Yasumaru; 橋本, 誠. A novel photoreactive ceramide analogue, which contains (3-trifluoromethyl) phenyldiazirinyl lipid and biotinylated sphingosine, was synthesized. The probe was recognized as an antigen by anti-ceramide antibody and as a substrate for sphingolipid ceramide N-deacylase. These results indicate that the probe may be useful as a photoaffinity-biotinylating agent in sphingolipid studies. Ano: 2008 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/2704 蛋白質、ペプチドの新規修飾法 OAK 橋本, 誠; Hashimoto, Makoto. Palavras-chave: ペプチド; 化学修飾; 機能解析. Ano: 2008 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/2039 Registros recuperados: 7 Primeira ... 1 ... Última

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