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| ESTEVAM,ELISÂNGELA B.B.; DEUS,ISABELLA P.B. DE; SILVA,VANESSA P. DA; SILVA,ELIZABETH A.J. DA; ALVES,CASSIA C.F.; ALVES,JOSÉ MILTON; CAZAL,CRISTIANE M.; MAGALHÃES,LIZANDRA G.; PAGOTTI,MARIANA C.; ESPERANDIM,VIVIANE R.; SOUZA,ALEX F.; MIRANDA,MAYKER L.D.. |
| ABSTRACT Leishmaniasis and trypanosomiasis are globally widespread parasitic diseases which have been responsible for high mortality rates. Since drugs available for their treatment are highly hepatotoxic, nephrotoxic and cardiotoxic, adherence to therapy has been affected. Thus, the search for new, more effective and safer drugs for the treatment of these diseases is necessary. Natural products have stood out as an alternative to searching for new bioactive molecules with therapeutic potential. In this study, the chemical composition and antiparasitic activity of the essential oil from Protium ovatum leaves against trypomastigote forms of Trypanosoma cruzi and the promastigote forms of Leishmania amazonensis were evaluated. The essential oil was promising... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Trypanosoma cruzi; Leishmania amazonensis; Essential oil; Protium ovatum; Parasitic diseases. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000603005 |
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| VALADARES,ANNA CAROLINA F.; ALVES,CASSIA CRISTINA F.; ALVES,JOSÉ MILTON; DE DEUS,ISABELLA P.B.; DE OLIVEIRA FILHO,JOSEMAR G.; DOS SANTOS,TAINÁ CAROLINE L.; DIAS,HERBERT JÚNIOR; CROTTI,ANTÔNIO EDUARDO M.; MIRANDA,MAYKER L.D.. |
| Abstract Even though essential oils from Piper aduncum (Piperaceae) have different biological activities, little is known about their application to agricultural areas. White mold is a plant disease caused by the phytopathogen Sclerotinia sclerotiorum, which needs to be controlled by alternative measures. This study aimed at evaluating the effect of essential oils from P. aduncum leaves (PL-EO) and inflorescences (PI-EO) on the mycelial growth of S. sclerotiorum. Essential oils from P. aduncum were obtained by hydrodistillation by a Clevenger-type apparatus while their chemical composition was analyzed by GC-MS and GC-FID. Piperitone (23.4 %), myristicin (12.4 %), terpinen-4-ol (12.3 %), β-caryophyllene (7.2 %), α-humulene (6.9 %), germacrene-D (6.9 %) and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Piper aduncum; Essential oils; Piperitone; Antifungal activity; Sclerotinia sclerotiorum. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000602691 |
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