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General aspects of muscle glucose uptake Anais da ABC (AABC)
ALVIM,RAFAEL O.; CHEUHEN,MARCEL R.; MACHADO,SILMARA R.; SOUSA,ANDRÉ GUSTAVO P.; SANTOS,PAULO C.J.L..
Glucose uptake in peripheral tissues is dependent on the translocation of GLUT4 glucose transporters to the plasma membrane. Studies have shown the existence of two major signaling pathways that lead to the translocation of GLUT4. The first, and widely investigated, is the insulin activated signaling pathway through insulin receptor substrate-1 and phosphatidylinositol 3-kinase. The second is the insulin-independent signaling pathway, which is activated by contractions. Individuals with type 2 diabetes mellitus have reduced insulin-stimulated glucose uptake in skeletal muscle due to the phenomenon of insulin resistance. However, those individuals have normal glucose uptake during exercise. In this context, physical exercise is one of the most important...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Diabetes; Exercise; Glucose uptake; Diet; Hypoglycemic drugs.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000100351
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Longitudinal study of the sympathovagal balance in women submitted to bariatric surgery Anais da ABC (AABC)
LUCAS,CRISTINA M.S.; ZANIQUELI,DIVANEI; ALVIM,RAFAEL O.; MIGUEL,GUSTAVO P.S.; MILL,JOSÉ GERALDO.
Abstract Studies have shown improvement of the cardiac autonomic balance in post-bariatric patients. Most of these studies included patients using drugs interfering in the autonomic nervous system. This study assessed the time course of changes in the sympathovagal balance after bariatric surgery (Roux-en-Y gastric bypass) in 26 women free from drugs. A 10-min electrocardiographic recording was obtained at baseline and at 3 and 6 months after surgery. Temporal and spectral domains of heart rate variability were analysed. The time domain components of cardiac vagal modulation increased progressively after surgery. In the frequency domain, high frequency power increased from 24.9 at baseline (18.0 to 46.3) to 44.5 at 3 months (23.4 to 65.6), and 54.1 at 6...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bariatric surgery; Autonomic control; Heart rate variability; Vagus outflow.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652020000100907
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