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Virological suppression in children and adolescents is not influenced by genotyping, but depends on optimal adherence to antiretroviral therapy BJID
Abreu,Juliana Costa de; Vaz,Sara Nunes; Martins Netto,Eduardo; Brites,Carlos.
ABSTRACT Objective: To evaluate the virological outcomes in children and adolescents infected with HIV-1 in Salvador, Bahia according to genotyping results. Methods: We retrospectively evaluated the rates of virological suppression of children and adolescents submitted to HIV-1 genotyping test from January/2008 to December/2012. The participants were followed in the two referral centers for pediatric AIDS care, in Salvador, Brazil. Resistance mutations, drug sensitivity profiles, and viral subtypes were analyzed using the Stanford HIV-1 Drug Resistance Database. Adherence was estimated by drugs withdrawal at pharmacies of the two sites. Results: 101 subjects were included: 35 (34.6%) were drug-naïve, and the remaining 66 were failing ART. In drug-naïve...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Children; Virological suppression; Genotyping; Adherence.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000300219
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