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Liposome and Their Applications in Cancer Therapy BABT
Pandey,Himanshu; Rani,Radha; Agarwal,Vishnu.
ABSTRACT Liposomes, the vesicles of phospholipid bilayer, can encapsulate both hydrophilic and lipophilic drugs and protect them from degradation. Liposomes have been extensively studied and continue to create intense interest in research since their discovery in the mid-1960s. Since then, liposomes have been considered to be the most successful nanocarriers for drug deliver and have made their way to the market. Currently, a number of liposomal formulations are on the marker for cancer treatment and many more are in pipe line. This review discusses about the liposome components, methods of preparation, drug encapsulation mechanism and the potential therapeutic applications of liposomes in cancer therapy.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Liposomes; Drug delivery; Cancer; Doxil; LipoDox; Myocet.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100303
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Nanoparticle-based drug delivery systems: promising approaches against infections BABT
Ranghar,Shweta; Sirohi,Parul; Verma,Pritam; Agarwal,Vishnu.
Despite the fact that many new drugs and technologies have been developed to combat the infectious diseases, these have continued to be global health challenges. The use of conventional antimicrobial agents against these infections is always associated with problems such as the development of multiple drug resistance and adverse side effects. In addition, the inefficient traditional drug delivery system results in inadequate therapeutic index, low bioavailability of drugs and many other limitations. In this regard, antimicrobial nanoparticles and nanosized drug delivery carriers have emerged as potent effective agents against the infections. Nanoparticles have unique properties owing to their ultra small and controllable size such as high surface area,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antimicrobial Nanoparticles; Drug Resistance; Drug Delivery System; Infection; Metal and Metal Oxide.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132014000200008
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