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| Maria Alice Ornellas Pereira; Alfredo Pereira Jr. |
| Advancement of research on the neurobiology of the schizophrenic brain has revealed a complex of factors, from genetic tendencies affecting the development of brain structure to functional impairment caused by defective molecular signaling. Recently, the attention of psychiatrists and mental health professionals has been directed to the presence of cognitive deficits, responsible for most of the obstacles to the social insertion of patients.The schizophrenic person has a difficulty to manage the flux of consciousness in social interactions. We address this difficulty with the Flower Arrangement Workshop, a methodology of Psycho-Social Rehabilitation that reduces the vulnerability of the schizophrenic in the social environment. The workshop was offered... |
| Tipo: Presentation |
Palavras-chave: Neuroscience. |
| Ano: 2008 |
URL: http://precedings.nature.com/documents/1497/version/1 |
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| Alfredo Pereira Jr. |
| In perceptual processes, signals carrying information about a stimulus are transmitted through multiple processing lines to populations of receptive neurons and thalamocortical circuits, leading to the formation of a spatial ensemble of local field potentials. This paper addresses the problem of how the brain integrates patterns embodied in local fields to (re)construct the stimulus in a conscious episode. Four examples of human perception are given to illustrate the requirements of the integrative process. Considering the strategic position of astrocytes, mediating somatic signals carried by blood flow and information carried by the neuronal network, as well as their intrinsic information processing capabilities, these cells are in an adequate condition... |
| Tipo: Manuscript |
Palavras-chave: Neuroscience. |
| Ano: 2011 |
URL: http://precedings.nature.com/documents/6484/version/1 |
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| Alfredo Pereira Jr; Fábio Augusto Furlan. |
| Conscious perceptual processing involves the sequential activation of cortical networks at several brain locations, and the onset of oscillatory synchrony affecting the same neuronal population. How do the earlier activated circuits sustain their excitation to synchronize with the later ones? We call such a sustaining process "meta-potentiation", and propose that it depends on neuro-astroglial interactions. In our proposed model, attentional cholinergic and stimulus-related glutamatergic inputs to astroglia elicit the release of astroglial glutamate to bind with neuronal NMDA receptors containing the NR2B subunit. Once calcium channels are open, slow inward currents activate the CaM/CaMKII complex to phosphorylate AMPA receptors in a... |
| Tipo: Manuscript |
Palavras-chave: Neuroscience. |
| Ano: 2007 |
URL: http://precedings.nature.com/documents/760/version/1 |
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| Alfredo Pereira Jr. |
| In this work I attempt to justify the claim that the discovery of statistically relevant brain correlates of consciousness supports Non-Reductive Physicalism. First I distinguish the main varieties of Reductive and Non-Reductive Physicalism, selecting the right one that is benefited by progress in brain sciences. Second, I discuss epistemological problems in the search of brain correlates of consciousness, focusing on the simultaneous occurrence of conscious activity, known by means of subjective report, and the corresponding brain activity, registered with the help of technology. Finally, I argue – using Salmon´s concept of Statistical Explanation - that statistics affords a distinction of causal (physical) from casual (illusory)... |
| Tipo: Manuscript |
Palavras-chave: Neuroscience. |
| Ano: 2012 |
URL: http://precedings.nature.com/documents/6969/version/1 |
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