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Expansion of gd T cells in patients infected with cutaneous leishmaniasis with and without glucantime therapy BJID
Darabi,Haideh; Abolhassani,Mohsen; Kariminia,Amina; Alimohammadian,Mohammad H..
The expansion of <FONT FACE=Symbol>gd </font>T cells in patients with active cutaneous leishmaniasis, with or without glucantime therapy, was investigated. Twenty patients with local cutaneous leishmaniasis including glucantime-treated (n=10) and untreated (n=10) patients were selected. The controls were healthy individuals (n=10) living in endemic areas. Whole blood was obtained and the T cell subpopulations were analyzed by flow cytometry. Significantly more <FONT FACE=Symbol>gd</FONT> CD3+ T cells were observed in untreated patients (15.9% ± 5.9), when compared with glucantime-treated patients (4.6% ± 1.4) and controls (5.3% ± 2.3). On the other hand, when the percentages of ab CD3+ T-cells were analyzed different results were...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cutaneous leishmaniasis; Gamma-delta T cells; Glucatime therapy.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000500007
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