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Atrophy of the Nitrergic Myenteric Neurons in the Descending Colon Rats Submitted to Protein and Vitamin Deficiency International Journal of Morphology
Araújo,Eduardo José de Almeida; Hermes,Catchia; Miranda Neto,Marcílio Hubner de; Almeida,Elton Carlos de; Sant'Ana,Débora de Mello Gonçales.
Effects of protein and B-complex vitamin deficiency were assessed with respect to the morphometry of myenteric neurons in the descending colon of adult rats. Sixteen animals were divided into two groups: Control Group (CG, n=8) and Experimental Group (EG, n=8). The CG received 22% protein chow and the EG received 4% protein chow for 120 days. The descending colon was submitted to NADH- and NADPH-diaphorase technique in order to evidence nervous cells in the whole mounts preparations. In the EG, NADH-d positive neurons presented reduced nuclei, while NADPH-d positive neurons showed atrophy of the soma area (~41.7%) inducing an increase of the proportion occupied by the nucleus inside in the soma of these cells.
Tipo: Journal article Palavras-chave: Malnutrition; Large intestine; Enteric nervous system; Myenteric plexus; Neural plasticity.
Ano: 2009 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000300047
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Hepatitis C disease burden and strategies for elimination by 2030 in Brazil. A mathematical modeling approach BJID
Benzaken,Adele Schwartz; Girade,Renato; Catapan,Elisa; Pereira,Gerson Fernando Mendes; Almeida,Elton Carlos de; Vivaldini,Simone; Fernandes,Neide; Razavi,Homie; Schmelzer,Jonathan; Ferraz,Maria Lucia; Ferreira,Paulo Roberto Abrão; Pessoa,Mario Guimarães; Martinelli,Ana; Souto,Francisco José Dutra; Walsh,Nick; Mendes-Correa,Maria Cassia.
ABSTRACT Introduction and aim: Hepatitis C is a key challenge to public health in Brazil. The objective of this paper was to describe the Brazilian strategy for hepatitis C to meet the 2030 elimination goal proposed by World Health Organization (WHO). Methods: A mathematical modeling approach was used to estimate the current HCV-infected Brazilian population, and to evaluate the relative costs of two different scenarios to address HCV disease burden in Brazil: (1) if no further changes are made to the HCV treatment program in Brazil; (2) where the WHO targets for 2030 elimination are met through diagnosis and treatment efforts peaking before 2024. Results: An anti-HCV prevalence of 0.53% was calculated for the total population. It was estimated that the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hepatitis C; Hepatitis C elimination; Hepatitis C disease burden; Brazil.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702019000300182
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