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| Lopes,A.J.; Marinho,C.L.; Alves,U.D.; Gonçalves,C.E.A.; Silva,P.O.; Botelho,E.C.; Bedirian,R.; Soares,A.R.; Maioli,M.C.P.. |
| Sickle cell anemia (SCA) causes dysfunction of multiple organs, with pulmonary involvement as a major cause of mortality. Recently, there has been growing interest in the nitrogen single-breath washout (N2SBW) test, which is able to detect ventilation heterogeneity and small airway disease when the results of other pulmonary function tests (PFTs) are still normal. Thus, the objectives of the present study were to assess the heterogeneity in the ventilation distribution in adults with SCA and to determine the association between the ventilation distribution and the clinical, cardiovascular, and radiological findings. This cross-sectional study included 38 adults with SCA who underwent PFTs, echocardiography, computed tomography (CT), and 6-min walk test. To... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Sickle cell anemia; Respiratory mechanics; Respiratory function tests; Ventilation; Exercise. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000800607 |
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