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| Fernandes,Thiago de Salazar e; Silva,Isvânia Maria Serafim da; Moraes,Renato Barros; Aguiar,Leandro Álvaro de Alcântara; Amaral,Ademir; Barbosa,Catão Temístocles; Nogueira,Romildo de Albuquerque. |
| This study investigated the dynamical process of chromosome condensation after colcemid treatment. Two pairs of human chromosomes, #2 and #3, were highlighted for the accurate identification by fluorescence in situ hybridization (FISH). A computerized image analysis system was used to measure the lengths of the two pairs of chromosomes averaged over 50 metaphases of different cultures with colcemid (0.5 µg/mL) added either at 3 or 48 h of a total 72 h culture period. For determining whether the process of chromosome condensation was chaotic or random, the algorithm of Detrended Fluctuation Analysis (DFA) was used. In order to evaluate the power of the method, the data were shuffled and DFA was performed again. It was found that colcemid prolonged treatment... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Non-linear dynamics; Chaos; Chromosome condensation; Colcemid. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132013000100011 |
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| Amaral,Ademir; Itié,Christian; Bok,Bernard. |
| The objective of this work was to evaluate radiation doses delivered to technologists engaged in different tasks involving positron emission tomography (PET) studies with FDG (fluorodeoxyglucose). This investigation was performed in two French nuclear medicine departments, which presented significant differences in their arrangements and radiation safety conditions. Both centers administered about 300 MBq per PET/CT study, although only one of them is a dedicated clinical PET center. Dose equivalent Hp(10) and skin dose Hp(0.07) were measured using Siemens electronic personnel dosimeters. For assessment dose absorbed by hands during drawing up of tracer and injection into the patient, a Polimaster wristwatch gamma dosimeter was employed. Absorbed dose and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Electronic Dosimeters; Radioprotection; Technologists; PET. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000600016 |
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| Amaral,Ademir. |
| Biological dosimetry (biodosimetry) is based on investigations of induced biological effects (biomarkers) in order to correlate them with radiation dose. Among the indicators employed in biodosimetry, scoring of chromosome aberrations is the most reliable method to quantify individual exposure to ionizing radiation. The technique, applied to circulating lymphocytes, has been developed into a routine procedure to evaluate the dose in the case of real or suspected accidental exposure. Considering the radiosensitivity of lymphocytes in vitro and in vivo as being the same, the dose effect relationship obtained after in vitro irradiation of blood has been widely used, with medico-legal value, for evaluating individual radiation exposure. This report presents an... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Biodosimetry; Physical dosimetry; Biomarkers; Chromosome aberrations. |
| Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132002000500017 |
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