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Hydroxylation of 1,8-cineole by Mucor ramannianusand Aspergillus niger BJM
Ramos,Aline de Souza; Ribeiro,Joyce Benzaquem; Teixeira,Bruna Gomes; Ferreira,José Luiz Pinto; Silva,Jefferson Rocha de A.; Ferreira,Alexandre do Amaral; Souza,Rodrigo Octavio Mendonça Alves de; Amaral,Ana Claudia F..
The monoterpenoid 1,8-cineole is obtained from the leaves of Eucalyptus globulus and it has important biological activities. It is a cheap natural substrate because it is a by-product of the Eucalyptuscultivation for wood and pulp production. In this study, it was evaluated the potential of three filamentous fungi in the biotransformation of 1,8-cineole. The study was divided in two steps: first, reactions were carried out with 1,8-cineole at 1 g/L for 24 h; afterwards, reactions were carried out with substrate at 5 g/L for 5 days. The substrate was hydroxylated into 2-exo-hydroxy-1,8-cineole and 3-exo-hydroxy-1,8-cineole by fungi Mucor ramannianus and Aspergillus niger with high stereoselectivity. Trichoderma harzianum was also tested but no...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Biotransformation monoterpene 1; 8-cineole Mucor ramannianus Aspergillus niger.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000100261
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