Within the UniProt consortium, the UniProtKB/Swiss-Prot knowledge base provides the international community with a stable, comprehensive, fully classified, richly and accurately annotated protein sequence database that is fully operable with other databases. Annotation relates to function(s) of the protein (their catalytic activity and the corresponding metabolic pathway(s) in which the protein may be involved), their cellular location, their interactions with other cellular components, etc. 

It is challenging to unify the way we annotate proteins, to ensure consistency and to describe data unambiguously. It is also highly valuable both for querying the database and for analyzing high-throughput data (expression data for... |