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| Kohn,LK; Foglio,MA; Rodrigues,RA; Sousa,IM de O; Martini,MC; Padilla,MA; Lima Neto,DF de; Arns,CW. |
| ABSTRACTAvian metapneumovirus (aMPV) is a negative-sense single-stranded RNA enveloped virus of the Metapneumovirus genus belonging to theParamyxoviridae family. This virus may cause significant economic losses to the poultry industry, despite vaccination, which is the main tool for controlling and preventing aMPV. The aim of this study was to evaluate the antiviral activity of extracts of four different native plants of the Brazilian Cerrado against aMPV. The antiviral activity against aMPV was determined by titration. This technique measures the ability of plant extract dilutions (25 to 2.5 µg mL-1) to inhibit the cytopathic effect (CPE) of the virus, expressed as inhibition percentage (IP). The maximum nontoxic concentration (MNTC) of the extracts used... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antiviral; Avian metapneumovirus; Gaylussacia brasiliensis; Arrabidaea chica; Virola sebifera; Aspidosperma tomentosum.. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2015000300275 |
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| Orsi,MA; Doretto Júnior,L; Reischak,D; Silva,LHA da; Spilki,FR; Buzinaro,MG; Arns,CW. |
| Intracerebral pathogenicity index (ICPI) and mean death time (MDT) were determined using commercial live vaccines against Newcastle disease available in Brazil. The ICPI profiles obtained for B1 vaccine strains were nonvirulent and varied from 0 to 0.19, and their MDT was 104-116 hours. The LaSota strains had an ICPI varying between 0.02 and 0.37 and MDT from 92 to 116 hours. ICPI and MDT for the Clone 30 were 0.11 and 104 hours, respectively. For Ulster vaccines, ICPI and MDT were 0 and >150 hours; for VG-GA was 0.03 and 140 hours; and for C2, 0.04 and >144 hours. Eye drop vaccination and IM challenge, at the 1st week and the 4th week, respectively, resulted in highest protection for B1 (95-100%) and LaSota (90-100%) strains. The variability in... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Newcastle disease virus (NDV) vaccines; Intracerebral pathogenicity index (ICPI); Mean death time (MDT). |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2009000200009 |
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