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Hepatitis B virus genotyping in chronic hepatitis B patients in southwestern Saudi Arabia BJID
Asaad,Ahmed Morad; Al-Ayed,Mohamed Saeed Zayed; Aleraky,Mohamed; Qureshi,Mohamed Ansar.
ABSTRACTThe distribution of hepatitis B virus genotypes in Saudi Arabia is largely unknown. To the best of our knowledge there are no data available about HBV genotypes in southwestern region of the country. This study aimed to determine the epidemiologic distribution of hepatitis B virus genotypes in chronic hepatitis B patients in southwestern region, and to verify possible correlations between these genotypes and the clinical symptoms. A total of 160 patients with chronic hepatitis B infection were enrolled in this study. Sera were tested for liver function tests, hepatitis B virus markers and DNA load by standard procedures. HBV genotyping was performed by 2-tube nested PCR for determination of six genotypes (A-F). Genotype D was the most common, found...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Hepatitis B; HBV genotypes; Genotype D; Najran.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000500525
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