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Analgesic and antiinflammatory activities of the essential oil from Artemisia sieberi Besser BJPS
Pishgahzadeh,Elahe; Shafaroodi,Hamed; Asgarpanah,Jinous.
The analgesic activity of Artemisia sieberi oil was assessed by acetic acid-induced writhing test and Eddy’s hot plate method; while the acute anti-inflammatory effect was investigated by inflammatory paw edema test in rats. The administration rout of the essential oil, standard drugs and the vehicle used in all assays was intraperitoneal injection. The 1 and 2.5 mg/kg doses of the studied oil significantly decreased the number of acetic acid-induced writhes in mice. The dose of 1 mg/kg of the oil also exhibited a central analgesic effect as evidenced by a significant increase in reaction time at several time points after 15 min treatment in the hot plate method. In addition, the 1 mg/kg dose of the oil significantly reduced carrageenan induced paw edema...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Artemisia sieberi drug effects Essential oil/therapeutic use Volatile oils/therapeutic use Analgesics/administration and dosage Anti-Inflammatory Agents Administration & Dosage.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100579
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In vivo analgesic and anti-inflammatory effects of the essential oil from Tanacetum balsamita L. BJPS
Sharif,Maryam; Najafizadeh,Parvaneh; Asgarpanah,Jinous; Mousavi,Zahra.
Tanacetum balsamita locally called Shahesparam is an aromatic plant that grows widely in Azerbaijan Province, Iran. Due to the widespread use of T. balsamita as a pain killer and relief of inflammatory based disorders in Iranian folk medicine and considering the high content of essential oil in T. balsamita aerial parts, we were prompted to investigate the anti-nociceptive and anti-inflammatory properties of T. balsamita essential oil (TBEO) for the first time. The carrageenan-induced Paw Edema was used for inflammation evaluation in rat, and hot-plate method was used for pain assessment in mice. Different doses of TBEO were administered. Morphine and Mefenamic acid were used as the standard drugs in anti-nociceptive and anti-inflammatory evaluation tests,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Tanacetum balsamita; Essential oil; Analgesic; Antiinflammatory.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100556
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