SABIIA - Sistema Aberto e Integrado de Informação em Agricultura (Sabiia)

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BJID (2)

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	Athanazio,Daniel Abensur (2)
	Athanazio,Paulo Roberto Fontes (1)
	Cerqueira,Thaís Bandeira (1)
	Seguro,Antônio Carlos (1)
	Spichler,Anne Stambovsky (1)

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Info:eu-repo/semantics/article (2)

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2008 (2)

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Brazil (2)

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Renal involvement in leptospirosis: new insights into pathophysiology and treatment

BJID

Cerqueira,Thaís Bandeira; Athanazio,Daniel Abensur; Spichler,Anne Stambovsky; Seguro,Antônio Carlos.

Acute renal failure (ARF) is one of the most common complications of leptospirosis although the causal mechanisms are still unclear. Diverse mechanisms are implicated in leptospiral nephropathy and new data supports the role of peculiar ion transport defects. Besides antibiotic therapy, ARF management in leptospirosis requires dialytic therapy which is most efficient when started early. Dialysis is the standard supportive therapy even though recent evidence suggests clinical benefit from alternative treatments such as plasmapheresis and hemofiltration. Renal recovery is achieved soon after clinical improvement. The comprehension of the primary mechanisms of renal dysfunction will be helpful in the development of additional therapeutic tools for improving...

Tipo: Info:eu-repo/semantics/article

Palavras-chave: Leptospirosis; Kidney failure; Acute; Physiopathology; Dialysis.

Ano: 2008

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000300016

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