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	Provedor de dados BJPS (2) Autor Avari,Jasmine Gev (2) Chafle,Sandip Annaji (2) Gaikwad,Swati Sanjay (1) Mohite,Badrinath Pralhadrao (1) Morris,Princy Sunil (1) Somasundaram,Jayaprakash (1) Mais... Palavra-chave Bilayer tablets (1) Cefixime trihydrate (1) Dispersion time (1) Indion 204 (1) Ion exchange resin (1) Ofloxacin (1) Ofloxacin. (1) Orally disintegrating tablets (1) Sexually transmitted diseases/treatment (1) Tableting properties (1) Tulsion 335 (1) Wetting time (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2016 (1) 2012 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Development and evaluation of ofloxacin orally disintegrating tablets BJPS Mohite,Badrinath Pralhadrao; Chafle,Sandip Annaji; Somasundaram,Jayaprakash; Avari,Jasmine Gev. Bitter taste of ofloxacin, a broad spectrum bactericidal agent, is masked and orally disintegrating tablets were formulated. The bitter taste is masked by forming complex between drug and weak cation exchange resins, Tulsion 335 and Indion 204. Effect of pH and drug:resin ratio on the drug loading was studied. Maximum drug loading was observed at pH 6. Ratio of 1:2 of drug:resin masked almost complete bitterness of ofloxacin. Formation of complexes was confirmed by IR spectroscopy. Physical characterization of taste masked complexes was carried out. Present work envisages the taste masking of ofloxacin and development of orally disintegrating tablets. The effect of pH and resin quantities on drug loading were studied to find the optimum conditions of drug... Tipo: Info:eu-repo/semantics/article Palavras-chave: Dispersion time; Indion 204; Ion exchange resin; Ofloxacin; Orally disintegrating tablets; Tableting properties; Tulsion 335; Wetting time. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502012000200005 Development and evaluation of bilayer tablets of combination of antibiotics for the treatment of sexually transmitted disease BJPS Gaikwad,Swati Sanjay; Chafle,Sandip Annaji; Morris,Princy Sunil; Avari,Jasmine Gev. ABSTRACT The present research work was envisaged to develop bilayer tablets to improve therapeutic efficacy of antibiotic combination for the treatment of sexually transmitted diseases. The combination of two antibiotics i.e. cefixime trihydrate and ofloxacin were used for the preparation of bilayer tablets which act against genito-urinary infections. The formulations comprise of cefixime trihydrate as immediate release layer formulated using different superdisintegrants and ofloxacin as extended release layer containing HPMC K100M. Evaluation of bilayer tablets were performed for the immediate release cefixime layer and sustain release ofloxacin layer with optimization of excipients. The immediate release layer of cefixime showed complete release within... Tipo: Info:eu-repo/semantics/article Palavras-chave: Sexually transmitted diseases/treatment; Bilayer tablets; Cefixime trihydrate; Ofloxacin.. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502016000300555 Registros recuperados: 2 Primeira ... 1 ... Última

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