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	Provedor de dados BJPS (2) Autor Araújo,Magali Benjamim de (2) Azevedo,Roberta de Cássia Pimentel (2) Bonfilio,Rudy (2) Favoretto,Lívia Botacini (1) Oliveira,Diego Borges de (1) Oliveira,Érika de Fátima Silva (1) Pereira,Gislaine Ribeiro (1) Ribeiro,Gislaine Pereira (1) Mais... Palavra-chave Direct UV spectrophotometry (1) Dissolution kinetics (1) First-derivative UV spectrophotometry (1) Losartan potassium (1) Meloxicam/dissolution (1) Spectrophotometry (1) Tablet pharmaceutical forms/dissolution test (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2010 (1) 2009 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Dissolution test optimization for meloxicam in the tablet pharmaceutical form BJPS Oliveira,Érika de Fátima Silva; Azevedo,Roberta de Cássia Pimentel; Bonfilio,Rudy; Oliveira,Diego Borges de; Ribeiro,Gislaine Pereira; Araújo,Magali Benjamim de. Meloxicam is a broadly used drug in the therapeutics for the osteoarthritis and rheumatoid arthritis treatments in adults, and it is available in the Brazilian market, as tablet and capsule pharmaceutical forms. The present work aimed to establish conditions for accomplishment of the dissolution test of 15 mg meloxicam tablets (A and B test products), compared with the reference product, since there is no monograph about dissolution assays for meloxicam in official summaries. To optimize the conditions several parameters were tested and, according to obtained results, the use of pH 7.5 phosphate buffer (900mL, at 37 ± 0.5ºC) as dissolution medium, paddle method (apparatus 2), stirring speed of the dissolution medium at 100 rpm and collect time of 60... Tipo: Info:eu-repo/semantics/article Palavras-chave: Meloxicam/dissolution; Dissolution kinetics; Tablet pharmaceutical forms/dissolution test; Spectrophotometry. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000100008 Comparative study of analytical methods by direct and first-derivative UV spectrophotometry for evaluation of losartan potassium in capsules BJPS Bonfilio,Rudy; Favoretto,Lívia Botacini; Pereira,Gislaine Ribeiro; Azevedo,Roberta de Cássia Pimentel; Araújo,Magali Benjamim de. Losartan potassium is an antihypertensive non-peptide agent, which exerts its action by specific blockade of angiotensin II receptors. The aim of the present study was the validation and application of analytical methods for the quality control of losartan potassium 50 mg in pharmaceutical capsules, using direct and first-derivative UV spectrophotometry. Based on losartan potassium spectrophotometric characteristics, a signal at 205 nm of the zero-order spectrum and a signal at 234 nm of the first-derivative spectrum, were found adequate for quantification. The results were used to compare these instrumental techniques. The linearity between the signals and concentrations of losartan potassium in the ranges of 3.0-7.0 mg L-1 and 6.0-14.0 mg L-1 for direct... Tipo: Info:eu-repo/semantics/article Palavras-chave: Losartan potassium; Direct UV spectrophotometry; First-derivative UV spectrophotometry. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000100017 Registros recuperados: 2 Primeira ... 1 ... Última

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