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Association of vincristine sulfate on therapeutic management of canine immune-mediated thrombocytopenia: a case report MV&Z
Baltazar, Fabio Navarro; Sena, Alex Lafarti de; Augusto, Cecília F. B.; Chemin, Andréa; Bearl, Carla Alice; Quinzani, Marcelo.
Immune-mediated thrombocytopenia, platelet destruction mediated by humoral and cellular responses, is frequently observed in dogs, especially in middle-age females of spaniels and Doberman breeds. The first line therapy involves the administration of corticosteroids in immunosuppressive doses and, in refractory cases, the pharmacological combination with other immunomodulatory agents seems often necessary. This case report describes the successful combination of vincristine sulfate to glucocorticoids (Dexamethasone) during the hospitalization of a dog with primary immune-mediated thrombocytopenia and related spontaneous bleeding, and discusses the therapeutic modalities in the literature.
Tipo: Info:eu-repo/semantics/article
Ano: 2015 URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/25560
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Association of vincristine sulfate on therapeutic management of canine immune-mediated thrombocytopenia: a case report MV&Z
Baltazar, Fabio Navarro; Sena, Alex Lafarti de; Augusto, Cecília F. B.; Chemin, Andréa; Bearl, Carla Alice; Quinzani, Marcelo.
Immune-mediated thrombocytopenia, platelet destruction mediated by humoral and cellular responses, is frequently observed in dogs, especially in middle-age females of spaniels and Doberman breeds. The first line therapy involves the administration of corticosteroids in immunosuppressive doses and, in refractory cases, the pharmacological combination with other immunomodulatory agents seems often necessary. This case report describes the successful combination of vincristine sulfate to glucocorticoids (Dexamethasone) during the hospitalization of a dog with primary immune-mediated thrombocytopenia and related spontaneous bleeding, and discusses the therapeutic modalities in the literature.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Thrombocytopenia; Autoimmunity; Dogs trombocitopenia; Autoimunidade; Cães.
Ano: 2015 URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/25560
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Clinical description and laboratory findings of bufotoxin canine intoxication (Rhinella icterica) (Anura: Bufonidae): case report MV&Z
Baltazar, Fabio Navarro; Augusto, Cecília de Faria Brito; Carminato, Carla; Faria, Paula Catarina de Oliveira; Berl, Carla Alice.
Despite of the high frequency of intoxications in the small animal practice, amphibian accidents are considered medical emergencies due to the high toxic potential of their venom, which tends to direct the clinical course of the intoxicated patient for cardiovascular and neurological pathophysiological events. The present study aims to describe the clinical and laboratory alterations observed in a dog poisoned by frog venom identified as Rhinella icterica (Anura: Bufonidae), through the diagnostic confirmation made by the identification of the amphibian on the images obtained by the tutors. The early institution of immediate (clinical stabilization) and late (intensive therapy) therapeutic strategies, as well as the staging of injuries in other organs and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bufo marinus; Bufotoxins; Bufodienolides; Bufotenins; Bufo marinus; Bufotoxinas; Bufodienolídeos; Bufoteninas.
Ano: 2019 URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/37919
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