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| Queiroz-Telles,Flávio; Silva,Nanci; Carvalho,Miriam M.; Alcântara,Ana Paula; Matta,Daniel da; Barberino,Maria G.; Bartczak,Sergio; Colombo,Arnaldo Lopes. |
| This study was a non-comparative multicenter clinical trial to evaluate the efficacy and tolerability of itraconazole oral solution 200 mg/day (100 mg twice a day in the fasting state) for the treatment of oropharyngeal candidiasis in AIDS patients. We included 50 patients who were treated and followed for up to 3 weeks after ending therapy in the analysis. Mycological cures at the end of therapy occurred in 20/50 patients (40%), but colonization by Candida sp. was recorded in 42/50 (84%) by the end of follow-up. A high rate of clinical response was observed in 46/50 (92%), and the response was sustained for up to 21 days after stopping therapy in 24/46 patients (52%). Clinical relapses were documented among 22 patients, but all causative fungal organisms... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: AIDS; Candidiasis; Itraconazole. |
| Ano: 2001 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702001000200003 |
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