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	Provedor de dados BJID (1) Autor Barcelona,Laura (1) Cané,Alejandro (1) Curcio,Daniel (1) Fernández,Francisco (1) Stamboulian,Daniel (1) Palavra-chave Off-label (1) Tigecycline (1) Ventilator-associated pneumonia (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2008 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Indications of a new antibiotic in clinical practice: results of the tigecycline initial use registry BJID Curcio,Daniel; Fernández,Francisco; Cané,Alejandro; Barcelona,Laura; Stamboulian,Daniel. Tigecycline is the first of a new class of antibiotics named glycylcyclines and it was approved for the treatment of complicated intra-abdominal infections and complicated skin and skin structure infections. Notwithstanding this, tigecycline's pharmacological and microbiological profile which includes multidrug-resistant pathogens encourages physicians' use of the drug in other infections. We analyzed, during the first months after its launch, the tigecycline prescriptions for 113 patients in 12 institutions. Twenty-five patients (22%) received tigecycline for approved indications, and 88 (78%) for "off label" indications (56% with scientific support and 22% with limited or without any scientific support). The most frequent "off label" use was ventilator... Tipo: Info:eu-repo/semantics/article Palavras-chave: Tigecycline; Off-label; Ventilator-associated pneumonia. Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000300007 Registros recuperados: 1 Primeira ... 1 ... Última

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