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	Provedor de dados BJMBR (2) Autor Barral,A. (2) Adorno,E. (1) Albuquerque,A. (1) Barral Netto,M. (1) Barral-Netto,M. (1) Brodskyn,C. (1) Cardoso,S.A. (1) Carvalho,E.M. (1) Gonçalves,M.S. (1) Queiroz,I.L. (1) Reis,M.G. dos (1) Sant'Ana,A. (1) Strapazoni,A.C. (1) Zanetti,A. (1) Mais... Palavra-chave Cytokines (1) Human leishmaniasis (1) IL-10 (1) IL-12 (1) Immunoregulation (1) Interleukin 8 (1) Sickle cell syndromes (1) Vaso-occlusive crisis (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2001 (1) 1998 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Human_Leishmaniasis@cytokines.bahia.br BJMBR Barral-Netto,M.; Brodskyn,C.; Carvalho,E.M.; Barral,A.. The cell-mediated immune response is critical in the resistance to and recovery from leishmaniasis. Cytokines are central elements in mounting an immune response and have received a great deal of attention in both human and experimental leishmaniasis. IFN-<FONT FACE="Symbol">g</font> is responsible for macrophage activation leading to leishmanicidal mechanisms. Understanding the balance of cytokines that lead to enhanced production of or synergize with IFN-<FONT FACE="Symbol">g</font>, and those cytokines that counterbalance its effects is fundamental for developing rational immunotherapeutic or immunoprophylactic approaches to leishmaniasis. Here we focus on the cytokine balance in human leishmaniasis, particularly IL-10 as an... Tipo: Info:eu-repo/semantics/article Palavras-chave: Cytokines; Human leishmaniasis; Immunoregulation; IL-12; IL-10. Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000100021 Interleukin 8 as a vaso-occlusive marker in Brazilian patients with sickle cell disease BJMBR Gonçalves,M.S.; Queiroz,I.L.; Cardoso,S.A.; Zanetti,A.; Strapazoni,A.C.; Adorno,E.; Albuquerque,A.; Sant'Ana,A.; Reis,M.G. dos; Barral,A.; Barral Netto,M.. Sickle cell disease has a worldwide distribution and is a public health problem in Brazil. Although vaso-occlusive crisis (VOC) is one of the most important clinical features of the disease, there are still several steps of its pathogenesis which are unknown. The increase of the chemotactic factor interleukin 8 (IL-8) has been reported to be involved in sickle cell disease crisis, but this has not been demonstrated conclusively. In the present study we analyzed serum IL-8 levels by ELISA and hematological parameters and hemoglobin patterns by standard techniques in 23 (21 SS and 2 SC) Brazilian patients with sickle cell syndromes during VOC caused by different inducing factors, 22 (21 SS and 1 SC) sickle cell patients out of crisis, and 11 healthy... Tipo: Info:eu-repo/semantics/article Palavras-chave: Interleukin 8; Sickle cell syndromes; Vaso-occlusive crisis. Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001001000011 Registros recuperados: 2 Primeira ... 1 ... Última

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