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|  |  | Gayoso,Regina; Dalcolmo,Margareth; Braga,José Ueleres; Barreira,Draurio. |  | ABSTRACT  Objectives To determine the main predictors of death in multidrug-resistant (MDRTB) patients from Brazil.  Design Retrospective cohort study, a survival analysis of patients treated between 2005 and 2012.  Results Of 3802 individuals included in study, 64.7% were men, mean age was 39 (1-93) years, and 70.3% had bilateral pulmonary disease. Prevalence of human immunodeficiency virus (HIV) was 8.3%. There were 479 (12.6%) deaths. Median survival time was 1452 days (4 years). Factors associated with increased risk of death were age greater than or equal to 60 years (hazard rate [HR] = 1.6, confidence interval [CI] = 1.15-2.2), HIV co-infection (HR = 1.46; CI = 1.05-1.96), XDR resistance pattern (HR = 1.74, CI = 1.05-2.9), beginning of treatment... |  
| Tipo: Info:eu-repo/semantics/article | Palavras-chave: Survival; Tuberculosis multidrug-resistant; Tuberculosis; Death. |  
| Ano: 2018 | URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000400305 |  |  |  |  |  |