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Production and characterization of lipid microparticles produced by spray cooling encapsulating a low molar mass hydrophilic compound Ciênc. Tecnol. Aliment.
Leonel,Alda Jusceline; Chambi,Hulda Noemi Mamani; Barrera-Arellano,Daniel; Pastore,Heloise Oliveira; Grosso,Carlos Raimundo Ferreira.
The objective of this research was to produce and characterize lipid particles (MpLs) that may be used as carriers of high amounts of hydrophilic core and evaluate the influence of the core amount on the performance of lipid microparticles. The MpLs were produced by spray cooling from solid and liquid lipid mixtures (stearic and oleic fatty acids and partly hydrogenated vegetable fat) containing glucose solution as core and soy lecithin as surfactant. The performance of MpLs was evaluated by means of the effective amount of encapsulated core, the core amount present on the surface of MpLs (superficial glucose) and the core release profile in aqueous solution. Morphological observations showed that MpLs presented spherical shape and a rugged and continuous...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Lipid microparticles; Spray cooling; Hydrophilic core release.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612010000100040
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