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The domestic pig (Sus scrofa domestica) as a model for evaluating nutritional and metabolic consequences of bariatric surgery practiced on morbid obese humans Ciencia e Investigación Agraria
Gandarillas,Mónica; Bas,Fernando.
The prevalence of obesity has increased dramatically over the last 20 years. Moreover, morbid obese patients routinely suffer from serious medical problems, especially cardiovascular disease. Medical therapy for morbid obesity offers no substantial long-term benefit, and thus the first choice therapy for severe obesity is effectively surgery. Gastrointestinal surgery for obesity, also called bariatric surgery, alters the digestive process by limiting food intake and facilitating malabsorption of nutrients from the diet. This arricie reviews the types and evolution of morbid obesity surgery performed in humans and proposes the pig model as an alternative when practicing new surgical techniques or improving actual procedures, as well as to evaluate the...
Tipo: Journal article Palavras-chave: Bariatric surgery; Human obesity; Obesity; Pig nutrition; Swine nutrition.
Ano: 2009 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-16202009000200002
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Nutrient absorption, feed intake and liveweight change as a consequence of Roux-en-Y gastric bypass with increasing alimentary limb lengths in the pig model Ciencia e Investigación Agraria
Gandarillas,Mónica; Boz,Camilo; Barrales,Luis; Hodgkinson,Suzanne Marie; Bas,Fernando.
Roux-en Y gastric bypass (RYGBP) combines a restrictive and malabsortive component of the digestive system. Metabolic outcomes of increasing the latter, is a matter of research interest. The aim of this study was to evaluate the nutritional consequences of RYGBP with different alimentary limb lengths using a pig model. Twenty-six pigs were randomly assigned to four laparoscopic procedures: RYGBP with 300 cm of alimentary limb (T300); RYGBP with 600 cm (T600); RYGBP with 900 cm (T900); sham operation (TS). RYGBP consisted of creating a proximal gastric pouch with a 300, 600 and 900 cm alimentary limb. Sham operation was performed by bowel transections and reanastomosis in the ileum and proximal jejunum together with gastrotomy and closure. Animals were...
Tipo: Journal article Palavras-chave: Gastric bypass; Roux-en-Y; Pig nutrition; Obesity.
Ano: 2011 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-16202011000100003
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