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	Provedor de dados BJPS (1) Autor Ansari,Muhammad Tayyab (1) Atique,Shabbar (1) Bashir,Farooq (1) Hussain,Talib (1) Shah,Syed Nisar Hussain (1) Shahzad,Yasser (1) Mais... Palavra-chave Dihydroartemisinin (DHA)/taste masking (1) Granules/coating (1) Medicines/coating (1) Thermogravimetric analysis/medicines analysis (1) X-ray diffraction/medicines analysis (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2011 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última The evaluation of coated granules to mask the bitter taste of dihydroartemisinin BJPS Shahzad,Yasser; Shah,Syed Nisar Hussain; Atique,Shabbar; Ansari,Muhammad Tayyab; Bashir,Farooq; Hussain,Talib. The purpose of this study was to mask the bitter taste imparted by dihydroartemisinin (DHA) by the use of different coating materials. Trial-1 and trial-2 were conducted to prepare the DHA granules. The granules produced from trial-1 were irregular in shape and smaller in size while the trial-2 granules were more regular and larger in size. The granules obtained from both trials were then coated with two different coating methods, namely A and B, depending upon coating material. The trial-2 granules showed better flow properties than trial-1 granules. In vitro dissolution studies in phosphate buffer at pH 6.8 revealed that granules of trial-2B released only 34% ± 3 DHA in two minutes compared with trial-1A (57% ± 2), trial-1B (48% ± 2) and trial-2A (53% ±... Tipo: Info:eu-repo/semantics/article Palavras-chave: Medicines/coating; Granules/coating; Dihydroartemisinin (DHA)/taste masking; Thermogravimetric analysis/medicines analysis; X-ray diffraction/medicines analysis. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000200013 Registros recuperados: 1 Primeira ... 1 ... Última

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