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	Provedor de dados Nature Precedings (9) Autor Basil Horst (9) Bernd Kastenholz (9) Jürgen Horst (9) Palavra-chave Neuroscience (9) Pharmacology (9) Tipo do documento Manuscript (9) Ano 2011 (9) País United Kingdom (9)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 9 Primeira ... 1 ... Última Can Plant-Made Copper Chaperones Heal Early Alzheimer’s Disease? Nature Precedings Bernd Kastenholz; Basil Horst; Jürgen Horst. Commercially available medicinal plant extracts such as Ginkgo biloba leaf extract show no consistent pattern of clinical benefit for people with dementia or cognitive impairment, and have been suggested to be toxic to cells at higher doses. However, medicinal plants may contain other more efficient bioactive molecules apart from the well-known flavonoids and terpenoids. Therapeutic recombinant proteins, plant-made copper chaperone for superoxide dismutase (CCS) derived from Ginkgo biloba leaves, may establish and maintain physiologic Cu levels through restoration and modulation of biometal metabolism in organ systems of younger Alzheimer patients (> 50 years). Medications developed from plant-made copper chaperone proteins may delay progression... Tipo: Manuscript Palavras-chave: Neuroscience; Pharmacology. Ano: 2011 URL: http://precedings.nature.com/documents/5907/version/6 Can Plant-Made Copper Chaperones Heal Early Alzheimer’s Disease? Nature Precedings Bernd Kastenholz; Basil Horst; Jürgen Horst. Commercially available medicinal plant extracts such as Ginkgo biloba leaf extract show no consistent pattern of clinical benefit for people with dementia or cognitive impairment, and have been suggested to be toxic to cells at higher doses. However, medicinal plants may contain other more efficient bioactive molecules apart from the well-known flavonoids and terpenoids. Therapeutic recombinant plant-made copper chaperone for superoxide dismutase (CCS) derived from Ginkgo biloba leaves may establish and maintain physiologic Cu levels through restoration and modulation of biometal metabolism in organ systems of younger Alzheimer patients (> 50 years). Medications developed from plant-made copper chaperone proteins may delay progression during early... Tipo: Manuscript Palavras-chave: Neuroscience; Pharmacology. Ano: 2011 URL: http://precedings.nature.com/documents/5907/version/4 Can Plant-Made Copper Chaperones Heal Early Alzheimer’s Disease? Nature Precedings Bernd Kastenholz; Basil Horst; Jürgen Horst. Commercially available medicinal plant extracts such as Ginkgo biloba leaf extract show no consistent pattern of clinical benefit for people with dementia or cognitive impairment, and have been suggested to be toxic to cells at higher doses. However, medicinal plants may contain other more efficient bioactive molecules apart from the well-known flavonoids and terpenoids. Therapeutic recombinant plant-made copper chaperone for superoxide dismutase (CCS) derived from Ginkgo biloba leaves may establish and maintain physiologic Cu levels through restoration and modulation of biometal metabolism in organ systems of younger Alzheimer patients (> 50 years). Medications developed from plant-made copper chaperone proteins may delay progression during early... Tipo: Manuscript Palavras-chave: Neuroscience; Pharmacology. Ano: 2011 URL: http://precedings.nature.com/documents/5907/version/3 Can Plant-Made Copper Chaperones Heal Early Alzheimer’s Disease? Nature Precedings Bernd Kastenholz; Basil Horst; Jürgen Horst. Commercially available medicinal plant extracts such as Ginkgo biloba leaf extract show no consistent pattern of clinical benefit for people with dementia or cognitive impairment, and have been suggested to be toxic to cells at higher doses. However, medicinal plants may contain other more efficient bioactive molecules apart from the well-known flavonoids and terpenoids. Therapeutic recombinant plant-made copper chaperone for superoxide dismutase (CCS) derived from Ginkgo biloba leaves may establish and maintain physiologic Cu levels through restoration and modulation of biometal metabolism in organ systems of younger Alzheimer patients (> 50 years). Medications developed from plant-made copper chaperone proteins may delay progression during early... Tipo: Manuscript Palavras-chave: Neuroscience; Pharmacology. Ano: 2011 URL: http://precedings.nature.com/documents/5907/version/5 Can Plant-Made Copper Chaperones Heal Early Alzheimer’s Disease? Nature Precedings Bernd Kastenholz; Basil Horst; Jürgen Horst. Commercially available medicinal plant extracts such as Ginkgo biloba leaf extract show no consistent pattern of clinical benefit for people with dementia or cognitive impairment, and have been suggested to be toxic to cells at higher doses. However, medicinal plants may contain other more efficient bioactive molecules apart from the well-known flavonoids and terpenoids. Therapeutic recombinant proteins, plant-made copper chaperone for superoxide dismutase (CCS) derived from Ginkgo biloba leaves, may establish and maintain physiologic Cu levels through restoration and modulation of biometal metabolism in organ systems of younger Alzheimer patients (> 50 years). Medications developed from plant-made copper chaperone proteins may delay progression... Tipo: Manuscript Palavras-chave: Neuroscience; Pharmacology. Ano: 2011 URL: http://precedings.nature.com/documents/5907/version/8 Can Plant-Made Copper Chaperones Heal Early Alzheimer’s Disease? Nature Precedings Bernd Kastenholz; Basil Horst; Jürgen Horst. Commercially available medicinal plant extracts such as Ginkgo biloba leaf extract show no consistent pattern of clinical benefit for people with dementia or cognitive impairment, and have been suggested to be toxic to cells at higher doses. However, medicinal plants may contain other more efficient bioactive molecules apart from the well-known flavonoids and terpenoids. Therapeutic recombinant proteins, plant-made copper chaperone for superoxide dismutase (CCS) derived from Ginkgo biloba leaves, may establish and maintain physiologic Cu levels through restoration and modulation of biometal metabolism in organ systems of younger Alzheimer patients (> 50 years). Medications developed from plant-made copper chaperone proteins may delay progression... Tipo: Manuscript Palavras-chave: Neuroscience; Pharmacology. Ano: 2011 URL: http://precedings.nature.com/documents/5907/version/7 Can Plant-Made Copper Chaperones Heal Early Alzheimer’s Disease? Nature Precedings Bernd Kastenholz; Basil Horst; Jürgen Horst. Therapeutic recombinant plant-made copper chaperone for superoxide dismutase (CCS) derived from Ginkgo biloba leaves may establish and maintain physiologic Cu levels through restoration and modulation of biometal metabolism in organ systems of younger Alzheimer patients (> 50 years). Medications developed from plant-made copper chaperone proteins may delay progression during early disease stages or even be a basis for a possible causal treatment of preclinical stages of Alzheimer’s disease by restoring cellular function of the CCS-SOD-1 mechanism and by preventing formation of Aβ plaques, a major putative factor involved in Alzheimer’s disease pathogenesis. Tipo: Manuscript Palavras-chave: Neuroscience; Pharmacology. Ano: 2011 URL: http://precedings.nature.com/documents/5907/version/1 Can Plant-Made Copper Chaperones Heal Early Alzheimer’s Disease? Nature Precedings Bernd Kastenholz; Basil Horst; Jürgen Horst. Commercially available medicinal plant extracts such as Ginkgo biloba leaf extract show no consistent pattern of clinical benefit for people with dementia or cognitive impairment, and have been suggested to be toxic to cells at higher doses. However, medicinal plants may contain other more efficient bioactive molecules apart from the well-known flavonoids and terpenoids. Therapeutic recombinant proteins, plant-made copper chaperone for superoxide dismutase (CCS) derived from Ginkgo biloba leaves, may establish and maintain physiologic Cu levels through restoration and modulation of biometal metabolism in organ systems of younger Alzheimer patients (> 50 years). Medications developed from plant-made copper chaperone proteins may delay progression... Tipo: Manuscript Palavras-chave: Neuroscience; Pharmacology. Ano: 2011 URL: http://precedings.nature.com/documents/5907/version/9 Can Plant-Made Copper Chaperones Heal Early Alzheimer’s Disease? Nature Precedings Bernd Kastenholz; Basil Horst; Jürgen Horst. Commercially available medicinal plant extracts such as Ginkgo biloba leaf extract show no consistent pattern of clinical benefit for people with dementia or cognitive impairment, and have been suggested to be toxic to cells at higher doses. However, medicinal plants may contain other more efficient bioactive molecules apart from the well-known flavonoids and terpenoids. Therapeutic recombinant plant-made copper chaperone for superoxide dismutase (CCS) derived from Ginkgo biloba leaves may establish and maintain physiologic Cu levels through restoration and modulation of biometal metabolism in organ systems of younger Alzheimer patients (> 50 years). Medications developed from plant-made copper chaperone proteins may delay progression during early... Tipo: Manuscript Palavras-chave: Neuroscience; Pharmacology. Ano: 2011 URL: http://precedings.nature.com/documents/5907/version/2 Registros recuperados: 9 Primeira ... 1 ... Última

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