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	Provedor de dados Electron. J. Biotechnol. (3) Autor Basri,Mahiran (3) Abdul Rahman,Mohd. Basyaruddin (1) Abdul Rahman,Raja Noor Zaliha Raja (1) Ahmad,Faujan Bin H (1) Ariff,Arbakariya (1) Bakar Salleh,Abu (1) Ebrahimpour,Afshin (1) Kamarudin,Nor Hafizah Ahmad (1) Mat Radzi,Salina (1) Moghaddam,Mansour Ghaffari (1) Mohammad,Rosfarizan (1) Rahman,Mohd Basyaruddin Abdul (1) Rahman,Raja Noor Zaliha Raja Abd (1) Salleh,Abu Bakar (1) Mais... Palavra-chave Artificial neural network (2) Acylation (1) Betulinic acid (1) Candida antarctica lipase (1) Enzymatic synthesis (1) Esterification (1) Immobilised lipase (1) Liquid wax ester (1) Modified response surface methodology (1) Novozym 435 (1) Oleyl oleate (1) Organic solvent tolerant (1) Thermostable (1) Mais... Tipo do documento Journal article (3) Ano 2011 (1) 2010 (1) 2005 (1) País Chile (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Artificial neural network modeling studies to predict the yield of enzymatic synthesis of betulinic acid ester Electron. J. Biotechnol. Moghaddam,Mansour Ghaffari; Ahmad,Faujan Bin H; Basri,Mahiran; Rahman,Mohd Basyaruddin Abdul. 3β-O-phthalic ester of betulinic acid was synthesized from reaction of betulinic acid and phthalic anhydride using lipase as biocatalyst. This ester has clinical potential as an anticancer agent. In this study, artificial neural network (ANN) analysis of Candida antarctica lipase (Novozym 435) -catalyzed esterification of betulinic acid with phthalic anhydride was carried out. A multilayer feed-forward neural network trained with an error back-propagation algorithm was incorporated for developing a predictive model. The input parameters of the model are reaction time, reaction temperature, enzyme amount and substrate molar ratio while the percentage isolated yield of ester is the output. Four different training algorithms, belonging to two classes, namely... Tipo: Journal article Palavras-chave: Acylation; Artificial neural network; Betulinic acid; Candida antarctica lipase; Enzymatic synthesis; Novozym 435. Ano: 2010 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582010000300003 High performance enzymatic synthesis of oleyl oleate using immobilised lipase from Candida antartica Electron. J. Biotechnol. Mat Radzi,Salina; Basri,Mahiran; Bakar Salleh,Abu; Ariff,Arbakariya; Mohammad,Rosfarizan; Abdul Rahman,Mohd. Basyaruddin; Abdul Rahman,Raja Noor Zaliha Raja. High performance enzymatic synthesis of oleyl oleate, a liquid wax ester was carried out by lipase-catalysed esterification of oleic acid and oleyl alcohol. Various reaction parameters were optimised to obtain high yield of oleyl oleate. The optimum condition to produce oleyl oleate was reaction time; 5 min, organic solvents of log P ≥ 3.5, temperature; 40-50ºC, amount of enzyme; 0.2-0.4 g and molar ratio of oleyl alcohol to oleic acid; 2:1. The operational stability of enzyme was maintained at >90% yield up to 9 cycles. Analysis of the yield of the product showed that at optimum conditions, >95% liquid wax esters were produced Tipo: Journal article Palavras-chave: Oleyl oleate; Immobilised lipase; Esterification; Liquid wax ester. Ano: 2005 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582005000300009 Lipase production and growth modeling of a novel thermophilic bacterium: Aneurinibacillus thermoaerophilus strain AFNA Electron. J. Biotechnol. Ebrahimpour,Afshin; Rahman,Raja Noor Zaliha Raja Abd; Kamarudin,Nor Hafizah Ahmad; Basri,Mahiran; Salleh,Abu Bakar. Aneurinibacillus thermoaerophilus strain AFNA as a novel isolated extracellular thermostable organic solvent tolerant lipase producing bacterium was employed in the present study. The lipase production of strain AFNA and its correlation with bacterial growth was studied via a modeling assessment by response surface methodology (RSM) and artificial neural network (ANN) techniques. The best achieved models were multilayer full feed forward incremental back propagation network and modified cubic response surface model (mRSM) using backward elimination. The highest lipase specific activity (13.1 Umg-1) and bacterial growth (OD600 = 3.0) were obtained at technically similar: growth temperature (53 and 53ºC), inoculum size (2.6 and 3.0%), agitation rate (118 and... Tipo: Journal article Palavras-chave: Artificial neural network; Modified response surface methodology; Thermostable; Organic solvent tolerant. Ano: 2011 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582011000400006 Registros recuperados: 3 Primeira ... 1 ... Última

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