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	Provedor de dados BJMBR (2) Autor Bernardes,N. (2) Brito,J.O. (2) De Angelis,K. (2) Irigoyen,M.C. (2) Belló-Klein,A. (1) Fernandes,T.G. (1) Figueroa,D. (1) Llesuy,S.F. (1) Ponciano,K. (1) Sanches,Í.C. (1) Mais... Palavra-chave Autonomic function (1) Blood pressure (1) Exercise training (1) Female rats (1) Fructose (1) Insulin resistance (1) Menopause (1) Oxidative stress (1) Parasympathetic nervous system (1) Simvastatin (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Info:eu-repo/semantics/other (1) Ano 2013 (1) 2008 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Pleiotropic effects of simvastatin in physically trained ovariectomized rats BJMBR Bernardes,N.; Brito,J.O.; Fernandes,T.G.; Llesuy,S.F.; Irigoyen,M.C.; Belló-Klein,A.; De Angelis,K.. This study tested the hypothesis that simvastatin treatment can improve cardiovascular and autonomic functions and membrane lipoperoxidation, with an increased effect when applied to physically trained ovariectomized rats. Ovariectomized rats were divided into sedentary, sedentary+simvastatin and trained+simvastatin groups (n = 8 each). Exercise training was performed on a treadmill for 8 weeks and simvastatin (5 mg/kg) was administered in the last 2 weeks. Blood pressure (BP) was recorded in conscious animals. Baroreflex sensitivity was evaluated by the tachycardic and bradycardic responses to BP changes. Cardiac vagal and sympathetic effects were determined using methylatropine and propranolol. Oxidative stress was evaluated based on heart and liver... Tipo: Info:eu-repo/semantics/article Palavras-chave: Menopause; Exercise training; Simvastatin; Autonomic function; Oxidative stress. Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000500447 Parasympathetic dysfunction is associated with insulin resistance in fructose-fed female rats BJMBR Brito,J.O.; Ponciano,K.; Figueroa,D.; Bernardes,N.; Sanches,Í.C.; Irigoyen,M.C.; De Angelis,K.. The objective of the present study was to identify metabolic, cardiovascular and autonomic changes induced by fructose overload administered in the drinking water of rats for 8 weeks. Female Wistar rats (200-220 g) were divided into 2 groups: control (N = 8) and fructose-fed rats (N = 5; 100 mg/L fructose in drinking water for 8 weeks). The autonomic control of heart rate was evaluated by pharmacological blockade using atropine (3 mg/kg) and propranolol (4 mg/kg). The animals were submitted to an intravenous insulin tolerance test (ITT) and to blood glucose measurement. The fructose overload induced a significant increase in body weight (~10%) and in fasting glycemia (~28%). The rate constant of glucose disappearance (KITT) during ITT was lower in... Tipo: Info:eu-repo/semantics/other Palavras-chave: Female rats; Fructose; Blood pressure; Insulin resistance; Parasympathetic nervous system. Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000900010 Registros recuperados: 2 Primeira ... 1 ... Última

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