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	Provedor de dados BABT (1) Autor Bhutia,Dawa (1) Pal,Joydeb (1) Rai,Benoy Kishore (1) Palavra-chave Biomarker (1) Channa punctatus (1) Cypermethrin (1) Cytochrome P450 (1) Fish (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2015 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Hepatic Cytochrome P450 as Biomarkers of Cypermethrin Toxicity in Freshwater Teleost, Channa punctatus (Bloch) BABT Bhutia,Dawa; Rai,Benoy Kishore; Pal,Joydeb. In this study, Channa punctatus was treated with sub-lethal concentration of cypermethrin (6.6 µg/L) for 5, 10 and 15 days and its effect on total CYP 450 and the activity of hepatic CYP450 isoforms measured. Total CYP450 content and CYP1A mediated EROD activity was significantly induced (p<0.05) in all three treated groups compared to control whereas only 15 days treated group showed significant induction in CYP2B mediated N,Ndimethylaniline demethylase activity. CYP2E1 mediated aniline hydroxylase activity showed only a marginal increase while there was inhibition of CYP3A4 mediated erythromycin demethylase activity. Liver somatic index (LSI) also showed a marginal increase in all the treated groups. Results showed differential induction of CYP1A,... Tipo: Info:eu-repo/semantics/article Palavras-chave: Cypermethrin; Cytochrome P450; Fish; Channa punctatus; Biomarker. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000100131 Registros recuperados: 1 Primeira ... 1 ... Última

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