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| Costa-Mugica,Ariana; Batista- Gonzalez,Ana Elsa; Mondejar,Diadelis; Soto-López,Yosdel; Brito-Navarro,Victor; Vázquez,Ana Maria; Brömme,Dieter; Zaldívar-Muñoz,Claudina; Vidal-Novoa,Alexis; Silva,Ana Mara de Oliveira e; Mancini-Filho,Jorge. |
| LDL oxidation and oxidative stress are closely related to atherosclerosis. Therefore, natural antioxidants have been studied as promising candidates. In the present study, the LDL oxidation inhibition activity of bioactive compounds from Halimeda incrassata seaweed. associated to antioxidant capacity, was evaluated in vitro. Experimental work was conducted with lyophilized aqueous extract and phenolic-rich fractions of the seaweed and their effect on LDL oxidation was evaluated using heparin-precipitated LDL (hep-LDL) with exposure to Cu2+ ions and AAPH as the free radical generator. H. incrassata had a protective effect for hep-LDL in both systems and the presence of phenolic compounds contributed to the activity where phenolic-rich fractions showed... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Halimeda incrassata/antioxidant properties; Antioxidants; Polyphenols; Lipoproteins/oxidation inhibition. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502012000100004 |
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