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| Registros recuperados: 10 | |
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| Ottobelli,Ivonei; Facundo,Valdir Alves; Zuliani,Juliana; Luz,Cleber Calado; Brasil,Henrique Otávio Braga; Militão,Júlio Sanches Linhares Teixeira; Braz-Filho,Raimundo. |
| Este trabalho relata o estudo químico de duas plantas medicinais da Amazônia: Philodendron scabrum K. krause (Araceae) e Vatairea guianensis Aubl. (Fabaceae). As composições dos óleos essenciais dos cipós de P. scabrum e dos frutos de V. guianensis, respectivamente, foram analisadas em CG-DIC e CG-EM. Os constituintes majoritários dos cipós de P. scabrum foram óxido de cariofileno (19,42%), α-copaeno (16,08%) e β-bisaboleno (10,01%); e nos frutos de V. guianensis foram o ácido (9Z)-octadecenoico (24,95%) e o ácido docosahexaenoico (24,17%). β-sitosterol e o alquilresorcinol 1-hexadecanoil-2,6-dihidroxibenzeno foram isolados do extrato etanólico dos cipós de P. scabrum; e do extrato etanólico dos frutos de V. guianensis, foram isoladas as antraquinonas... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Philodendron scabrum; Vatairea guianensis; Óleo essencial; Antraquinonas. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672011000300009 |
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| Carvalho,Mário G. de; Silva,Virginia C. da; Silva,Tânia M.S. da; Camara,Celso A.; Braz-Filho,Raimundo. |
| The reaction of the flavonol 3,7,3', 4'-tetra-O-methylquercetin (1) and of the isoflavone 7,4'-di-O-methylgenistein (2) with alkaline iodine in methanol afforded four new iodine derivatives: 8-iodo-5-hydroxy-3,7,3', 4'-tetramethoxy- flavone (1a) and 6-iodo-5-hydroxy-3,7,3', 4'-tetramethoxyflavone (1b) from 1; 2 afforded a mixture of two compounds, identified as a racemic mixture of (±)-trans-5-hydroxy-2,3,7,4'-tetramethoxy-8-iodo-isoflavanone (2a) and (±)-trans-5-hydroxy-2,3,7,4'-tetramethoxy-6,8-diiodo-isoflavanone (2b). The formation of these different products reveals a significant difference involving the chemical interaction between the reactive site of α, β-unsaturated ketones of flavonol and isoflavone under the tested reaction conditions (using... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Flavonol; Isoflavone; Iodoflavonoid; Iodoisoflavonoid; Iodine derivatives. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652009000100004 |
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| Vieira,Ivo J.C.; Medeiros,Walter L.B.; Monnerat,Cecilia S.; Souza,Jucimar J.; Mathias,Leda; Braz-Filho,Raimundo; Pinto,Angelo C.; Sousa,Priscila M.; Rezende,Claudia M.; Epifanio,Rosângela De A.. |
| The pharmacotherapyfor Alzheimer's disease (AD) includes the use of acetylcholinesterase inhibitors (AChEI). Recent investigations for novel AD therapeutic agents from plants suggested that Tabernaemontana genus is a promising source of novel anticholinesterasic indole alkaloids. In this work two fast screening techniques were combined in order to easily identify novel cholinesterase inhibitors (ChEI). Gas chromatography-mass spectrometry (GC-MS) of the less polar alkaloidic fractions obtained from the acid-base extraction of the stalk of T. laeta revealed thirteen monoindole alkaloids, four of them confirmed by co-injection with previously isolated alkaloids. The others were tentatively identified by mass fragmentation analysis. By gas chromatography with... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Tabernaemontana; Indole alkaloids; Cholinesterase inhibitor; Thin-layer chromatography assay; Ellman´s method; GC-MS. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652008000300003 |
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| Johann,Susana; Smânia-Jr,Artur; Pizzolatti,Moacir G.; Schripsema,Jan; Braz-Filho,Raimundo; Branco,Alexsandro. |
| A mixture of the two new flavonols 8-hydroxy-3, 4', 5, 6, 7-pentamethoxyflavone (1) and 8-hydroxy-3, 3', 4', 5, 6, 7-hexamethoxyflavone (2) was isolated from a commercial sample of Citrus aurantifolia. An array of one- (¹HNMR, {¹H}-13C NMR, and APT-13C NMR) and two-dimensional NMR techniques (COSY, NOESY, HMQC and HMBC) was used to achieve the structural elucidation and the complete ¹H and 13C chemical shift assignments of these natural compounds. In addition, the antifungal activity of these compounds against phytopathogenic and human pathogenic fungi was investigated. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Polymethoxyflavones; Antifungal activity; Citrus aurantifolia. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652007000200004 |
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| Branco,Alexsandro; Pinto,Angelo C.; Schripsema,Jan; Braz-Filho,Raimundo. |
| 2-acetyl physcion (2-acetyl-1,8-dihydroxy-6-methoxy-3-methyl-9,10-anthraquinone, 2), a rare anthraquinone, was isolated from Senna macranthera var. nervosa (Vogel) H.S. Irwin & Barneby (Fabaceae). The chemical structure was elucidated and all ¹H and 13C NMR chemical shifts were assigned by NMR one- (¹HNMR, {¹H}-13CNMR, and APT-13CNMR) and two (COSY, NOESY, HMQC and HMBC) dimensional of this natural compound. Furthermore, the minor anthraquinones chrysophanol (3), chrysophanol-8-methyl ether (4) and physcion (5) were characterized by GC-MS analysis. The occurrence of the anthraquinones 3-5 confirms that S. macranthera is a typical representative of the genus Senna. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Anthraquinone; 2-acetyl-physcion; Fabaceae; Senna acranthera. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652011000400003 |
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| Carlos,Lanamar de Almeida; Amaral,Kenas Aguiar da Silva; Vieira,Ivo José Curcino; Mathias,Leda; Braz-Filho,Raimundo; Samarão,Solange Silva; Vieira-da-Motta,Olney. |
| Staphylococci bacteria are involved in many human and animal infections and development of alternative antimicrobial drugs against pathogenic bacteria is of great interest to the pharmaceutical industry. This study investigated the in vitro effect of Rauvolfia grandiflora methanol extract (root bark fraction) (RGE) on the density of ATCC strains of Staphylococcus aureus and Staphylococcus epidermidis, and a clinical enterotoxin-producer, S. aureus bovine strain. The alkaloid, isoreserpiline, obtained from dichloromethane extract of R. grandiflora was ineffective against the strains tested. After incubation of staphylococci strains in the presence of 1.2 mg.mL-1 RGE, a significant inhibition of cell growth was observed using both spectrophotometry and ELISA... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rauvolfia grandiflora; Staphylococcus aureus; Enterotoxin; Antimicrobial activity. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822010000300011 |
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| Façanha,Arnoldo Rocha; Façanha,Anna Lvovna Okorokova; Olivares,Fábio Lopes; Guridi,Fernando; Santos,Gabriel de Araújo; Velloso,Ary Carlos Xavier; Rumjanek,Victor Marcos; Brasil,Felipe; Schripsema,Jan; Braz-Filho,Raimundo; Oliveira,Marco Antônio de; Canellas,Luciano Pasqualoto. |
| A bioatividade de ácidos húmicos (AH) isolados de lodo da estação de tratamento de esgoto (AHL) e de vermicomposto (AHV) foi avaliada pela ação dessas substâncias sobre o transporte de prótons através da membrana plasmática de células de raízes de café e milho e sua relação com o desenvolvimento dessas espécies. Houve estímulo da área superficial radicular em ambas as espécies cultivadas com ambos AH, mostrando uma concentração ótima em torno de 40 mg L-1. Nessa condição, os tratamentos com AHL e AHV estimularam a H+-ATPase de membrana plasmática em plântulas de café e milho. Os AHL foram mais efetivos na promoção desses efeitos do que os AHV. A modificação do perfil cromatográfico dos AH em solução antes e após o cultivo das plântulas revelou que a... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Zea mays; Coffea arabica; Lodo residual; Ácidos orgânicos; Vermicomposto. |
| Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-204X2002000900014 |
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| Barbosa-Filho,José Maria; Sampaio A Lima,Cláudia; Camorim,Elba Lúcia; de Sena,Kêsia Xisto FR; Almeida,Jackson Roberto GS; Vasconcelos L da-Cunha,Emídio; Silva,Marcelo S; Agra,Maria de Fátima; Braz-Filho,Raimundo. |
| We report morphodiagnosis, and phytochemical and antimicrobial investigations of Tabebuia aurea. It was noted that the leaves are compostas with anomocytic stomata only on the lower side; the vascular system is concentric andthe mesophyll arrangement is dorsiventral. From the stem bark eight compounds were isolated, including: lapachol, 3,4',5-trihydroxy-7-methoxyflavone, b-sitosterol, betulinic acid, p-anisic acid, veratric acid, methyl cinnamate and ethyl p-hydroxy-cinnamate. Antimicrobial assays showed growth inhibition the of Gram positive and Gram negative bacteria, alcohol-acid bacterium and fungi. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Tabebuia aurea; Bignoniaceae; Pharmacobotany; Lapachol; Chemical constituents; Antimicrobial activity. |
| Ano: 2004 |
URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1851-56572004000100027 |
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| Canellas,Luciano Pasqualoto; Espindola,José Antonio Azevedo; Rezende,Carlos Eduardo; Camargo,Plínio Barbosa de; Zandonadi,Daniel Basílio; Rumjanek,Victor Marcos; Guerra,José Guilherme Marinho; Teixeira,Marcelo Grandi; Braz-Filho,Raimundo. |
| Using herbaceous legumes in agricultural systems yields great quantities of plant residues, allowing changes in soil organic matter quality and content over the years. This study was conducted on an Ultisol, at Seropédica, RJ, Brazil, to evaluate the effects of different perennial herbaceous legumes on soil organic matter quality. A factorial scheme with three replications was used to evaluate the species: forage groundnut cv. BR-14951 (Arachis pintoi), tropical kudzu (Pueraria phaseoloides), and siratro (Macroptilium atropurpureum). After the first cut, each plot was divided into two subplots; plants were cut and left on the soil surface or cut and removed. Soil samples of a closed area covered by spontaneous vegetation (mainly C3 plants) or by Panicum... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: FTIR; Fluorescence; Humic acids; Humic substances; 13C. |
| Ano: 2004 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-90162004000100010 |
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| Registros recuperados: 10 | |
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