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| Batista-Neves,Susana; Quarantini,Lucas C.; Galvão-de Almeida,Amanda; Cardeal,Maurício; Lacerda,Acioly L.; Paraná,Raymundo; Reis de-Oliveira,Irismar; Bressan,Rodrigo A.; Miranda-Scippa,Angela. |
| The aim of our study was to determine the impact of psychiatric comorbidities on the health-related quality of life of HCV-infected patients. Assessment of clinical, socio-demographic and quality of life data of the patients followed up at a Hepatology unit was performed by using a standard questionnaire and the SF-36 instrument. Psychiatric diagnoses were confirmed by using the Mini International Neuropsychiatric Interview, Brazilian version 5.0.0 (MINI Plus). Evaluation using the MINI plus demonstrated that 46 (51%) patients did not have any psychiatric diagnosis, while 44 (49%) had at least one psychiatric diagnosis. Among patients with a psychiatric comorbidity, 26 (59.1%) had a current mental disorder, out of which 22 (84.6%) had not been previously... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Mental disorders; Quality of life; HCV. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000100009 |
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| Quarantini,Lucas C.; Cruz,Simone Cunha; Batista-Neves,Susana Carolina; Paraná,Raymundo; Miranda-Scippa,Ângela; Bressan,Rodrigo A.. |
| Pegylated Interferon-alpha, combined with ribavirin, gives high sustained virological response in patients with hepatitis C virus, an important public health problem and one of the most frequent chronic infectious diseases worldwide. Though it has therapeutic benefits, treatment with IFN-alpha may be complicated by various side effects, especially symptoms of major depression and acute mania. Psychosis is a rare side effect, and its management usually includes discontinuation of IFN-alpha. We report a case of psychotic disorder that occurred during therapy with pegylated Interferon-alpha given associated with ribavirin. After good response to psychiatric treatment, it became possible to finish the anti-viral therapy. |
| Tipo: Info:eu-repo/semantics/report |
Palavras-chave: Interferon-alpha; Hepatitis C; Psychosis. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000600010 |
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