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Candidemia epidemiology and susceptibility profile in the largest Brazilian teaching hospital complex BJID
Motta,Adriana Lopes; Almeida,Gisele Madeira Duboc de; Almeida Júnior,João Nóbrega de; Burattini,Marcelo Nascimento; Rossi,Flávia.
INTRODUCTION: Although the spectrum of fungi causing bloodstream fungal infections continues to expand, Candida spp. remains responsible for the majority of these cases. OBJECTIVE: The purpose of this study was to characterize the candidemia epidemiology, species distribution and antifungal susceptibility patterns at a Brazilian tertiary teaching public hospital with 2,500 beds. METHODS: Records from the microbiology laboratory were used to identify patients with positive blood cultures during 2006. The in vitro activity of amphotericin B, caspofungin, itraconazole, fluconazole, voricanozole, and posaconazole were determined using the Etest method. RESULTS: One hundred and thirty-six cases of candidemia were identified and 100 strains were available for...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Candidemia; Candida spp; Susceptibility testing; Candida epidemiology; Candida Etest; Antifungal susceptibility profile; Candida antifungal agents; Azoles.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000500004
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Analysis of antimicrobials' consumption profile in a University Hospital of Western Paraná, Brazil BJPS
Caldeira,Luciane de Fátima; Burattini,Marcelo Nascimento.
The objective of this study was to analyze the variation in antimicrobials' consumption and the costs related to their use at a University Hospital between 1999 and 2004. The annual consumption of nine antimicrobials, expressed in DDD/100 patients-day, and the direct costs with their acquisition were evaluated. Analysis of variance and regression techniques were used to compare data, considering a significance level of 5%. The most consumed antimicrobials were amikacin and ceftriaxone. In general, antimicrobials consumption, expressed in DDD/100 patients-day, increased from 9.21 in 1999 to 25.08 in 2004 (p<0.0001). When analyzing antimicrobial consumption as related to specific hospital units, the ICU showed the highest consumption followed by...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Medicines/Defined Daily Doses; Medicines/utilization; Antimicrobials/consumption; Pharmacoepidemiology.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000200015
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