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Martínez,Rodrigo; Dunner,Susana; Toro,Rubén; Tobón,Jaime; Gallego,Jaime; Cañón,Javier. |
The resistance/susceptibility of selected cattle breeds to brucellosis was evaluated in an F1 population generated by crossing animals classified as resistant (R) and susceptible (S) (R x R, R x S, S x R, S x S) based on challenges in vitro and in vivo. The association between single nucleotide polymorphisms identified in the coding region of the Slc11a1 gene and resistance/susceptibility was estimated. The trait resistance or susceptibility to brucellosis, evaluated by a challenge in vitro, showed a high heritable component in terms of additive genetic variance (h² = 0.54 ± 0.11). In addition, there was a significant association (p < 0.05) between the control of bacterial survival and two polymorphisms (a 3'UTR and SNP4 located in exon 10). The... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Blanco Orejinegro Creole breed; Brahman breed; Brucella abortus; Genetic resistance; Zebu. |
Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572010000300014 |
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