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	Provedor de dados BJMBR (3) Autor Campagnole-Santos,M.J. (3) Santos,R.A.S. (3) Alzamora,A.C. (2) Lima,W.G. (2) Silva,M.E. (2) Almeida,A.P. (1) Carneiro,C.M. (1) De Castro,U.G. (1) Frábregas,B.C. (1) Machado,R.P. (1) Madureira,M.M. (1) Maia,R.C.A. (1) Rodrigues,M.C. (1) Santos,R.J.S. (1) Soares,E.R. (1) Sousa,L.E. (1) Mais... Palavra-chave Baroreflex bradycardia (2) 2K1C renovascular hypertension (1) Angiotensin-(1-7) (1) Bradykinin (1) Bradykinin potentiation (1) Cardiac and renal remodeling (1) Coronary artery (1) Different exercise workload (1) Heart and kidney adaptations (1) L-NAME (1) Oxidative stress (1) Prostaglandins (1) Rat heart (1) Renovascular hypertension (1) Swimming (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Ano 2015 (1) 2011 (1) 2000 (1) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Angiotensin-(1-7) potentiates the coronary vasodilatatory effect of bradykinin in the isolated rat heart BJMBR Almeida,A.P.; Frábregas,B.C.; Madureira,M.M.; Santos,R.J.S.; Campagnole-Santos,M.J.; Santos,R.A.S.. It has been shown that angiotensin-(1-7) (Ang-(1-7)) infusion potentiates the bradykinin (BK)-induced hypotensive response in conscious rats. The present study was conducted to identify Ang-(1-7)-BK interactions in the isolated rat heart perfused according to the Langendorff technique. Hearts were excised and perfused through the aortic stump under a constant flow with Krebs-Ringer solution and the changes in perfusion pressure and heart contractile force were recorded. Bolus injections of BK (2.5, 5, 10 and 20 ng) produced a dose-dependent hypotensive effect. Ang-(1-7) added to the perfusion solution (2 ng/ml) did not change the perfusion pressure or the contractile force but doubled the hypotensive effect of the lower doses of BK. The BK-potentiating... Tipo: Info:eu-repo/semantics/article Palavras-chave: Angiotensin-(1-7); Bradykinin; Coronary artery; Rat heart; L-NAME; Prostaglandins; Bradykinin potentiation. Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000600012 Time-course effects of aerobic exercise training on cardiovascular and renal parameters in 2K1C renovascular hypertensive rats BJMBR Maia,R.C.A.; Sousa,L.E.; Santos,R.A.S.; Silva,M.E.; Lima,W.G.; Campagnole-Santos,M.J.; Alzamora,A.C.. Exercise training (Ex) has been recommended for its beneficial effects in hypertensive states. The present study evaluated the time-course effects of Ex without workload on mean arterial pressure (MAP), reflex bradycardia, cardiac and renal histology, and oxidative stress in two-kidney, one-clip (2K1C) hypertensive rats. Male Fischer rats (10 weeks old; 150–180 g) underwent surgery (2K1C or SHAM) and were subsequently divided into a sedentary (SED) group and Ex group (swimming 1 h/day, 5 days/week for 2, 4, 6, 8, or 10 weeks). Until week 4, Ex decreased MAP, increased reflex bradycardia, prevented concentric hypertrophy, reduced collagen deposition in the myocardium and kidneys, decreased the level of thiobarbituric acid-reactive substances (TBARS) in the... Tipo: Info:eu-repo/semantics/article Palavras-chave: 2K1C renovascular hypertension; Swimming; Baroreflex bradycardia; Heart and kidney adaptations; Oxidative stress. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015001101010 Cardiac and renal effects induced by different exercise workloads in renovascular hypertensive rats BJMBR Soares,E.R.; Lima,W.G.; Machado,R.P.; Carneiro,C.M.; Silva,M.E.; Rodrigues,M.C.; De Castro,U.G.; Santos,R.A.S.; Campagnole-Santos,M.J.; Alzamora,A.C.. We examined the effect of exercise training (Ex) without (Ex 0%) or with a 3% workload (Ex 3%) on different cardiac and renal parameters in renovascular hypertensive (2K1C) male Fisher rats weighing 150-200 g. Ex was performed for 5 weeks, 1 h/day, 5 days/week. Ex 0% or Ex 3% induced similar attenuation of baseline mean arterial pressure (MAP, 119 ± 5 mmHg in 2K1C Ex 0%, N = 6, and 118 ± 5 mmHg in 2K1C Ex 3%, N = 11, vs 99 ± 4 mmHg in sham sedentary (Sham Sed) controls, N = 10) and heart rate (HR, bpm) (383 ± 13 in 2K1C Ex 0%, N = 6, and 390 ± 14 in 2K1C Ex 3%, N = 11 vs 371 ± 11 in Sham Sed, N = 10,). Ex 0%, but not Ex 3%, improved baroreflex bradycardia (0.26 ± 0.06 ms/mmHg, N = 6, vs 0.09 ± 0.03 ms/mmHg in 2K1C Sed, N = 11). Morphometric evaluation... Tipo: Info:eu-repo/semantics/article Palavras-chave: Cardiac and renal remodeling; Baroreflex bradycardia; Different exercise workload; Renovascular hypertension. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000600011 Registros recuperados: 3 Primeira ... 1 ... Última

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