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| Torres,Thiago Silva; Cardoso,Sandra Wagner; Velasque,Luciane de Souza; Marins,Luana Monteiro Spindola; Oliveira,Marília Santini de; Veloso,Valdilea Gonçalves; Grinsztejn,Beatriz. |
| The introduction of highly active antiretroviral therapy during the 1990s was crucial to the decline in the rates of morbidity and death related to the acquired immunodeficiency syndrome (AIDS) and turned human immunodeficiency virus (HIV) infection into a chronic condition. Consequently, the HIV/AIDS population is becoming older. The aim of this study was to describe the immunological, clinical and comorbidity profile of an urban cohort of patients with HIV/AIDS followed up at Instituto de Pesquisa Clinica Evandro Chagas, Oswaldo Cruz Foundation in Rio de Janeiro, Brazil. Retrospective data from 2307 patients during January 1st, 2008 and December 31st, 2008 were collected. For continuous variables, Cuzick's non-parametric test was used. For categorical... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: HIV; AIDS; Aging; Elderly; Brazil; Comorbidity; HAART. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000300004 |
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| Torres,Thiago Silva; Cardoso,Sandra Wagner; Velasque,Luciane S.; Veloso,Valdilea G.; Grinsztejn,Beatriz. |
| Toxicity is the most frequently reported reason for modifying or discontinuing the first combined antiretroviral therapy regimens, and it can cause significant morbidity, poor quality of life and also can be an important barrier to adherence, ultimately resulting in treatment failure and viral resistance. Elderly patients with HIV/AIDS (≥50 years) may have a different profile in terms of treatment modification due to higher incidence of comorbidities and polypharmacy. The aim of this study was to describe the incidence of modifying or discontinuing first combined antiretroviral therapy regimen due to toxicity (TOX-MOD) during the first year of treatment at the IPEC – FIOCRUZ HIV/AIDS cohort, Rio de Janeiro, Brazil, stratified by age. Demographic, clinical... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: HIV; Toxicity; Aging; Antiretroviral. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000100034 |
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| Cardoso,Sandra Wagner; Torres,Thiago Silva; Santini-Oliveira,Marilia; Marins,Luana Monteiro Spindola; Veloso,Valdiléa Gonçalves; Grinsztejn,Beatriz. |
| The worldwide elderly population is expected to grow by an additional 694 million people by 2025. By that time, there will be approximately two billion elderly people in the world, most of whom (80%) will be living in developing countries. Based on recent estimates, this population will number over 40 million in 2030 in Brazil and a consequent increase in governmental spending for this population can be expected. Since highly active antiretroviral therapy became available in the mid-1990s, the life expectancy of people living with HIV has increased significantly. Approximately 12 million life years were added to the world between 1996 and 2008 as a consequence of wider access to highly active antiretroviral therapy. In Brazil, the incidence of AIDS among... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: HIV; AIDS; Aging; Elderly; Brazil; Comorbidity; HAART. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000400013 |
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