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Pereira,Leandro Cabral; Nogueira,Thaísa Amorim; Barbosa,Leandro Augusto de Oliveira; Calil-Elias,Sabrina; Castilho,Selma Rodrigues de. |
The rates of breast cancer mortality remain high in Brazil. Docetaxel is a semi-synthetic taxane used to treat various tumors, particularly tumors of the breast, lung and prostate. In this study ADR that occurred in 45 docetaxel users with breast cancer were surveyed. They were identified by type, causality (Naranjo algorithm and World Health Organization categories) and, if considered probable or defined, rated for severity according to SOBRAFO proposal (2007). A total of 325 ADR were observed: 165 in the first, 137 in the second and 23 in the third cycle. Fifty seven ADR were immediate and the others, late. Fatigue and exhaustion for more than five days, classified as Grade 3 by SOBRAFO (2007), were reported as the primary late RAM. There was no... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Docetaxel/adverse reactions; Drugs/adverse reactions; Breast Cancer/tretament/reactions. |
Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000300551 |
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Deutsch,Gabriela; Bokehi,Luciana Castilho; Silva,Ana Elisa Gonçalves Pereira Rodrigues; Guimarães Junior,Luiz Macieira; Rodrigues,Rogério; Esper,Luciana Maria Ramires; Gonzalez,Alice Gonçalves Martins; Paula,Geraldo Renato de; Castilho,Selma Rodrigues de; Teixeira,Lenise Arneiro. |
ABSTRACT The practice of immersion in burn patient has been abandoned in many parts of the world but in Brazil it is still common. The aim of this study was to ascertain if balneotherapy is a risk factor for Pseudomonas aeruginosa colonization in thermally injured patients. Eighteen patients from a Burn Center were studied for 14 weeks for Pseudomonas aeruginosa. Samples were collected by swabbing the exudate of wounds, before and after giving bath to the patients and from balneotherapy table. Pulsed-field gel electrophoresis was used to determine bacterial genetic relatedness. Thirty-seven P. aeruginosa isolates were detected from 292 swabs collected from patients' burn surface area and from the balneotherapy table. Profile analysis of P. aeruginosa DNA... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Pseudomonas aeruginosa/colonization; Burn patients; Balneotherapy; PFGE.. |
Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502016000100014 |
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