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| R odriguez,Andrea P.; Tsujigiwa,Hidetsugu; Gunduz,Mehmet; Cengiz,Beyhan; Nagai,Noriyuki; Tamamura,Ryo; Borkosky,Silvia S.; Takagi,Tohru; Inoue,Miho; Nagatsuka,Hitoshi. |
| Progenitor cells play an important biological role in tooth and bone formation, and previous analyses during bone and dentine induction have indicated that they may be a good alternative for tissue engineering. Thus, to clarify the influence of the microenvironment on protein and gene expression, MDPC-23 cells (mouse dental papilla cell line) and KUSA/A1 cells (bone marrow stromal cell line) were used, both in vitro cell culture and in intra-abdominal diffusion chambers implanted in 4-week-old male immunodefficient mice (SCID mice). Our results indicate that KUSA/A1 cells differentiated into osteoblast-like cells and induced bone tissue inside the chamber, whereas, MDPC-23 showed odontoblast-like characteristics but with a low ability to induce dentin... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: MDPC-23 cells; KUSA/A1 cells; Diffusion chamber; RT-PCR analysis; Immunohistochemical analysis. |
| Ano: 2009 |
URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452009000100005 |
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