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	Provedor de dados BJM (2) Autor Chauhan,Nitin M (2) Karuppayil,S Mohan (1) Karuppayil,S. Mohan (1) Routh,Madhushree M (1) Shinde,Ravikumar B (1) Palavra-chave Candida albicans (2) Alcohols (1) Antifungal antibiotics (1) Biofilms (1) Cancer drugs (1) Morphogenesis (1) Morphogenetic switching (1) Signalling (1) Yeast metabolism (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2013 (2) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Effect of alcohols on filamentation, growth, viability and biofilm development in Candida albicans BJM Chauhan,Nitin M; Shinde,Ravikumar B; Karuppayil,S. Mohan. In this study we report the potential of alcohols as morphogenetic regulators in Candida albicans. All the alcohols tested influenced various modes of growth like planktonic as well as biofilm forms. Viability was affected at high concentrations. Among the alcohols, the response of C. albicans to amyl alcohol (pentanol) was noteworthy. Amyl alcohol at a concentration 0.5% which was not inhibitory to growth and viability specifically inhibited morphogenetic switching from yeast to hyphal forms. It also inhibited normal biofilm development favoring yeast dominated biofilms. Based on this study we hypothesize that alcohols produced under anaerobic conditions may not favor biofilm development and support dissemination of yeast cells. Since anaerobic conditions... Tipo: Info:eu-repo/semantics/article Palavras-chave: Alcohols; Signalling; Morphogenesis; Biofilms; Yeast metabolism; Candida albicans. Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000400041 Cancer drugs inhibit morphogenesis in the human fungal pathogen, Candida albicans BJM Routh,Madhushree M; Chauhan,Nitin M; Karuppayil,S Mohan. Candida infections are very common in cancer patients and it is a common practice to prescribe antifungal antibiotics along with anticancer drugs. Yeast to hyphal form switching is considered to be important in invasive candidiasis. Targeting morphogenetic switching may be useful against invasive candidiasis. In this study, we report the antimorphogenetic properties of thirty cancer drugs. Tipo: Info:eu-repo/semantics/article Palavras-chave: Candida albicans; Morphogenetic switching; Cancer drugs; Antifungal antibiotics. Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000300029 Registros recuperados: 2 Primeira ... 1 ... Última

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