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One-pot synthesis of graphene-chitosan nanocomposite modified carbon paste electrode for selective determination of dopamine Electron. J. Biotechnol.
Liu,Chang; Zhang,Jing; Yifeng,E; Yue,Jingli; Chen,Lianshan; Li,Donghui.
Background A simple, rapid, low-cost and environmentally friendly method was developed to determine dopamine (DA) in the presence of ascorbic (AA) and uric acid (UA) based on a novel technique to prepare a graphene-chitosan (GR-CS) nanocomposite and modify it on the surface of carbon paste electrode (CPE). For our design, CS acts as a media to disperse and stabilize GR, and then GR plays a key role to selective and sensitive determination of DA. Results Under physiological conditions, the linear range for dopamine was determined from 1 × 10- 4 to 2 × 10- 7 mol/L with a good correlation coefficient of 0.9961 in the presence of 1000-fold interference of AA and UA. The detection limit was estimated to be 9.82 × 10- 8 mol/L (S/N = 3). In order to study the...
Tipo: Journal article Palavras-chave: Dopamine; Selective determination; Surface modification of carbon paste electrode; Technique of one-pot synthesis.
Ano: 2014 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582014000400007
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