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	Provedor de dados BJMBR (2) Autor Christoffolete,M.A. (2) Bianco,A.C. (1) Bocco,B.M. (1) Cysneiros,R.M. (1) Fernandes,G.W. (1) Grecco,S.S. (1) Lago,J.H.G. (1) Lancellotti,C.L. (1) Lorena,F.B. (1) Moriscot,A.S. (1) Ribeiro,M.O. (1) Romoff,P. (1) Mais... Palavra-chave Caffeic acid (1) Ferulic acid (1) Hypercaloric diet (1) Hypothyroidism (1) Metabolic syndrome (1) Obesity (1) Thyroid hormone (1) UCP3 (1) Uncoupling protein (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Info:eu-repo/semantics/other (1) Ano 2016 (1) 2004 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Combined treatment with caffeic and ferulic acid from Baccharis uncinella C. DC. (Asteraceae) protects against metabolic syndrome in mice BJMBR Bocco,B.M.; Fernandes,G.W.; Lorena,F.B.; Cysneiros,R.M.; Christoffolete,M.A.; Grecco,S.S.; Lancellotti,C.L.; Romoff,P.; Lago,J.H.G.; Bianco,A.C.; Ribeiro,M.O.. Fractionation of the EtOH extract from aerial parts of Baccharis uncinella C. DC. (Asteraceae) led to isolation of caffeic and ferulic acids, which were identified from spectroscopic and spectrometric evidence. These compounds exhibit antioxidant and anti-inflammatory properties and have been shown to be effective in the prevention/treatment of metabolic syndrome. This study investigated whether the combined treatment of caffeic and ferulic acids exhibits a more significant beneficial effect in a mouse model with metabolic syndrome. The combination treatment with caffeic and ferulic acids was tested for 60 days in C57 mice kept on a high-fat (40%) diet. The data obtained indicated that treatment with caffeic and ferulic acids prevented gain in body weight... Tipo: Info:eu-repo/semantics/article Palavras-chave: Obesity; Caffeic acid; Ferulic acid; Metabolic syndrome. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000300604 Hypercaloric cafeteria-like diet induced UCP3 gene expression in skeletal muscle is impaired by hypothyroidism BJMBR Christoffolete,M.A.; Moriscot,A.S.. The uncoupling protein UCP3 belongs to a family of mitochondrial carriers located in the inner mitochondrial membrane of certain cell types. It is expressed almost exclusively at high levels in skeletal muscle and its physiological role has not been fully determined in this tissue. In the present study we have addressed the possible interaction between a hypercaloric diet and thyroid hormone (T3), which are strong stimulators of UCP3 gene expression in skeletal muscle. Male Wistar rats weighing 180 ± 20 g were rendered hypothyroid by thyroidectomy and the addition of methimazole (0.05%; w/v) to drinking water after surgery. The rats were fed a hypercaloric cafeteria diet (68% carbohydrates, 13% protein and 18% lipids) for 10 days and sacrificed by... Tipo: Info:eu-repo/semantics/other Palavras-chave: Thyroid hormone; Hypothyroidism; Hypercaloric diet; Uncoupling protein; UCP3. Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000600019 Registros recuperados: 2 Primeira ... 1 ... Última

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