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Rotavirus in adults, Brazil, 2004–2011: G2P[4] dominance and potential impact on vaccination BJID
Luchs,Adriana; Cilli,Audrey; Morillo,Simone Guadagnucci; Carmona,Rita de Cassia Compagnoli; Timenetsky,Maria do Carmo Sampaio Tavares.
Objectives:The aim of this study was to monitor rotavirus (RV) infections in adults >18 years with acute gastroenteritis during 2004–2011 national Brazilian RV surveillance. In addition, to characterize the RV group A (RVA) strains in order to gain insight into the supposed vaccine selective pressure imposed to Brazilian children population.Methods:A total of 2102 convenient fecal specimens were investigated by ELISA, PAGE, and RT-PCR.Results:RV was detected in 203 (9.6%) of 2102 specimens, and showed a marked peak of detection in September. RVA infection was detected in 9.4% (197/2102) and RV group C (RVC) in 0.3% (6/2102). The most frequent genotypes detected in 2004 and 2005 were G9P[8] (38.5%; 5/13) and G1P[8] (54.5%; 6/11), respectively. The...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Rotavirus group A; Rotavirus group C; Adults; Vaccination; Brazil.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000100053
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Echovirus 6 associated to aseptic meningitis outbreak, in São Joaquim da Barra, São Paulo, Brazil BJM
Luchs,Adriana; Russo,Denise Hage; Cilli,Audrey; Costa,Fernanda Faria; Morillo,Simone Guadagnucci; Machado,Bráulio Caetano; Pellini,Alessandra Cristina Guedes; Carmona,Rita de Cássia Compagnoli; Timenetsky,Maria do Carmo Sampaio Tavares.
An aseptic meningitis outbreak occurred during a period from February to May 2004 in São Joaquim da Barra, a town in the northern region of São Paulo State. A total of 40 cases were reported to the Epidemiological Surveillance Center of São Paulo State. Cerebrospinal fluid samples obtained from 23 patients were sent to the Adolfo Lutz Institute for isolation of the virus. These samples were inoculated into RD, HEp2 and Vero cell lineages and those presenting a cytopathogenic effect were selected for analysis by indirect immunofluorescence assay (IFA), neutralization testing (Nt) and reverse transcriptase-polymerase chain reaction (RT-PCR). Cytopathogenic effects were observed in 52.2% (12/23) of these samples. All isolated viruses were identified as human...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Enterovirus surveillance; Echovirus 6; Aseptic meningitis.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822008000100007
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